This product is to be stored in room temperature.
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100 MG
₩192,444
About This Item
실험식(Hill 표기법):
C15H22O5
CAS Number:
Molecular Weight:
282.33
MDL number:
UNSPSC 코드:
12352205
PubChem Substance ID:
NACRES:
NA.79
추천 제품
Quality Level
분석
98%
양식
solid
광학 활성
[α]20/D +76°, c = 0.5 in methanol
mp
156-157 °C (lit.)
항생제 활성 스펙트럼
parasites
viruses
응용 분야
metabolomics
vitamins, nutraceuticals, and natural products
동작 모드
enzyme | inhibits
SMILES string
C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4
InChI
1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1
InChI key
BLUAFEHZUWYNDE-NNWCWBAJSA-N
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일반 설명
애플리케이션
Artemisinin has been used:
- in drug susceptibility assays[4]
- as a standard for its quantification from artemisinin from hairy roots[5]
- to check cell viability using 3-(4, 5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium bromide (MTT) assay[6]
- as an antimalarial agent to investigate the role of autophagy-related (ATG) genes throughout the P. falciparum asexual and sexual blood stages[7]
생화학적/생리학적 작용
Artemisinin (Qinghaosu), a sesquiterpene lactone, is a highly active anti-malarial (falciparum malaria) drug. Artemisinin is also an anthelmintic (parasitic worm) effective against the blood fluke, schistosomiasis.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Olivo Miotto et al.
Nature genetics, 45(6), 648-655 (2013-04-30)
We describe an analysis of genome variation in 825 P. falciparum samples from Asia and Africa that identifies an unusual pattern of parasite population structure at the epicenter of artemisinin resistance in western Cambodia. Within this relatively small geographic area
The multifunctional autophagy pathway in the human malaria parasite, Plasmodium falciparum
Cervantes S, et al.
Autophagy, 10(1), 80-92 (2014)
Antiprotozoal agents
Croft SL and Seifert K
Antibiotics and Chemotherapy, 29(10), 406-426 (2011)
Artemisinins: their growing importance in medicine
Krishna S, et al.
Trends in Pharmacological Sciences, 29(10), 520-527 (2008)
C J Paddon et al.
Nature, 496(7446), 528-532 (2013-04-12)
In 2010 there were more than 200 million cases of malaria, and at least 655,000 deaths. The World Health Organization has recommended artemisinin-based combination therapies (ACTs) for the treatment of uncomplicated malaria caused by the parasite Plasmodium falciparum. Artemisinin is a
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At what temperature do we store artemisinin
1 답변-
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Is there any expiry of this compound?
1 답변-
This product is not assigned an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
도움이 되었습니까?
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In what solvents is Product 361593, Artemisinin, soluble?
1 답변-
According to the chemicals encyclopedia published by the Royal Society of Chemistry, artemisinin is expected to be soluble in most aprotic solvents and slightly soluble in oil. Sigma-Aldrich tests the solubility of this product in chloroform at 25 mg/mL. Our quality control is also able to prepare a 0.5% solution in methanol in order to measure the optical rotation.
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