PHR1008

Ascorbic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

• 동의어(들): L-Ascorbic acid, L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
• 실험식(Hill 표기법): C₆H₈O₆
• CAS Number: 50-81-7
• Molecular Weight: 176.12
• Beilstein: 84272
• EC Number: 200-066-2
• MDL number: MFCD00064328
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329823039
• E 번호: E300
• NACRES: NA.24

속성

• Grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to BP 461; traceable to Ph. Eur. A1300000; traceable to USP 1043003
• API family: ascorbic acid
• 형태: solid
• CofA: current certificate can be downloaded
• 기술: HPLC: suitable; gas chromatography (GC): suitable
• mp: 190-194 °C (dec.)
• 응용 분야: food and beverages
• 형식: neat
• 저장 온도: 2-8°C
• SMILES string: OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
• InChI: 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
• InChI key: CIWBSHSKHKDKBQ-JLAZNSOCSA-N

설명

일반 설명

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ascorbic acid is a powerful antioxidant and is widely used in pharmaceutical formulations. It has proven to have a beneficial effect on age-related diseases such as cancer, atherosclerosis, ocular, neurodegenerative diseases, etc. It is mainly involved in the formation and maintenance of collagen. The prolonged deficiency of ascorbic acid in diet may result in scurvy.

애플리케이션

Ascorbic Acid may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using hydrophilic interaction chromatography.

생화학적/생리학적 작용

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

분석 메모

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAC2886 in the slot below. This is an example certificate only and may not be the lot that you receive.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable