M8506
Methimazole
analytical standard
동의어(들):
1-Methyl-2-mercaptoimidazole, MET, 1-Methyl-2-imidazolethiol, 2-Mercapto-1-methylimidazole
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C4H6N2S
CAS Number:
Molecular Weight:
114.17
Beilstein:
108646
EC Number:
MDL number:
UNSPSC 코드:
41116107
eCl@ss:
39161002
PubChem Substance ID:
NACRES:
NA.24
추천 제품
Grade
analytical standard
Quality Level
분석
≥99%
기술
HPLC: suitable
gas chromatography (GC): suitable
mp
144-147 °C (lit.)
응용 분야
cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary
형식
neat
SMILES string
CN1C=CNC1=S
InChI
1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI key
PMRYVIKBURPHAH-UHFFFAOYSA-N
유전자 정보
human ... TPO(7173)
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일반 설명
Methimazole belongs to the chemical class of thioureylene compounds, used as an anti-thyroid drug in the management of hyperthyroidism.
애플리케이션
Beclomethasone dipropionate analytical standard can be used as follows:
- Silver/graphene-modified carbon-paste electrode (AgGCPE) based electrochemical determination of methimazole
- Development of a surface-enhanced Raman scattering (SERS) based method to estimate propylthiouracil and methimazole using sodium alginate-protected silver nanoparticles as SERS substrate
- Detection of methimazole at ultra-trace limits using surface-enhanced Raman spectroscopy based on gold nanoparticles (AuNPs) substrate
- Quantitative analysis of human blood samples for methimazole using high-performance liquid chromatography-tandem mass spectrometric (HPLC-MS/MS) method
- Electrochemical determination of methimazole in pharmaceutical tablet and human blood serum samples by molecularly imprinted polymer (MIP)- pencil graphite electrode (PGE) based sensor
기타 정보
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Choose from one of the most recent versions:
이미 열람한 고객
Determination of methimazole in urine with the iodine-azide detection system following its separation by reversed-phase high-performance liquid chromatography
Zakrzewski R
Journal of Chromatography. B, Biomedical Applications, 869(1-2), 67-74 (2008)
David H Brann et al.
Science advances, 6(31) (2020-09-17)
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A key question is whether SARS-CoV-2 (CoV-2) - the causal agent in COVID-19 - affects olfaction directly, by infecting olfactory sensory neurons or their targets in
MMSPE-RP-HPLC method for the simultaneous determination of methimazole and selected metabolites in fish homogenates.
Hollosi L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(4), 921-924 (2004)
F S Boretti et al.
Journal of veterinary internal medicine, 27(2), 377-381 (2013-02-13)
Transdermal methimazole is an acceptable alternative to oral treatment for hyperthyroid cats. There are, however, no studies evaluating the duration of T4 suppression after transdermal methimazole application. Such information would be valuable for therapeutic monitoring. To assess variation in serum
Nicole R van Veenendaal et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(2), 684-691 (2012-11-15)
Antithyroid medications are the preferred therapy for the treatment of Graves' disease during pregnancy. Propylthiouracil (PTU) is favored over methimazole (MMI) due to potential teratogenic concerns with MMI. This study was to determine the teratogenic potential of MMI and PTU
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