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D6001

Sigma-Aldrich

Dextran sulfate sodium salt from Leuconostoc spp.

average mol wt >500,000 (dextran starting material), contains 0.5-2.0% phosphate buffer, pH 6-8

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12352201
NACRES:
NA.21

생물학적 소스

bacterial (Leuconostoc mesenteroides)

Quality Level

형태

powder

광학 활성

[α]/D 90 to 105 °, c = 6% (w/v) in water

분자량

average mol wt >500,000 (dextran starting material)

포함

0.5-2.0% phosphate buffer, pH 6-8

구성

Sulfur Content, 16.0-19.0%

색상

white to off-white

유용한 pH 범위

6.0-8.0 (1% in water)

solubility

H2O: 100 mg/mL

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일반 설명

Dextran sulfate is a negatively charged sulfated polysaccharide, which is produced by the esterification of dextran with chlorosulphonic acid. It has antiviral, anticoagulant and adjuvant properties. Dextran is used to treat hemorrhage, burns, surgery and trauma. It enhances blood flow and blocks erythrocyte aggregation. Dextran decreases the risk of thrombosis and postoperative pulmonary emboli. It acts as a ribonuclease inhibitor.

애플리케이션

Dextran sulfate sodium salt Leuconostoc spp has been used:
  • to delipidate fatty plasma(67)(70)
  • to induce inflammatory and carcinogenic response in the distal colon of rodents(68)
  • for the preparation of 3,4-ethylenedioxythiophene (EDOT)(69)

기타 정보

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Zora Djuric et al.
The Journal of nutritional biochemistry, 46, 90-99 (2017-05-10)
Dietary fish oils have potential for prevention of colon cancer, and yet the mechanisms of action in normal and tumor colon tissues are not well defined. Here we evaluated the impact of the colonic fatty acid milieu on the formation
Seda Onder et al.
Frontiers in pharmacology, 8, 713-713 (2017-10-27)
Hupresin is a new affinity resin that binds butyrylcholinesterase (BChE) in human plasma and acetylcholinesterase (AChE) solubilized from red blood cells (RBC). Hupresin is available from the CHEMFORASE company. BChE in human plasma binds to Hupresin and is released with
The Molecular Biology of Poliovirus (2012)
Delipidation of plasma has minimal effects on human butyrylcholinesterase
Onder S, et al.
Frontiers in Pharmacology, 9, 117-117 (2018)
PEDOT doped with algal, mammalian and synthetic dopants: polymer properties, protein and cell interactions, and influence of electrical stimulation on neuronal cell differentiation
Molino PJ, et al.
Biomaterials Science, 6(5), 1250-1261 (2018)

프로토콜

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

관련 콘텐츠

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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