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Merck
모든 사진(1)

문서

31395

Sigma-Aldrich

Dextran sulfate sodium salt from Leuconostoc spp.

Mr ~500,000

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12352201
NACRES:
NA.21

생물학적 소스

(Leuconostoc spp.)

형태

powder

분자량

Mr ~500,000

구성

Sulfur Content, 16.0-19.0% (dry basis)

제조업체/상표

EDQM

유용한 pH 범위

6.0-8.0 (10 g/L)

solubility

H2O: freely soluble 50 mg/mL, clear

음이온 미량물

chloride (Cl-): ≤100 mg/kg

양이온 미량물

Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤1000 mg/kg
Mg: ≤100 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

저장 온도

room temp

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애플리케이션

Dextran sulfate sodium salt from Leuconostoc sp. was used as a test compound for studying the heparin and dextran sulphate interaction with alkali ions. It was used for releasing DNA from DNA-histone complexes.

생화학적/생리학적 작용

Dextran is a mixture of glucose polymers of varying size and geometry. Dextran in the form of dextran sulfate acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength.The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.

제조 메모

prepared from dextran with Mr ~500,000

기타 정보

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Lisa Nebelin Hvidt et al.
Danish medical journal, 59(11), A4531-A4531 (2012-11-23)
Synthetic colloids are frequently used in fluid resuscitation of septic patients. Despite this, little is known about the potential side effects including the risk of renal failure and bleeding. As practice has changed, we performed a before-and-after study of fluid
Se Young Choi et al.
Journal of biomedicine & biotechnology, 2010, 943516-943516 (2010-03-20)
A total of 28 male BALB/c mice (average weight 20.7 +/- 1.6 g) were divided into 4 treatment groups and fed a commercial diet (A), a commercial diet + induced colitis by dextran sodium sulfate (DSS) (B), Inonotus obliquus (IO)
Heparin and dextran sulfate antagonize PGI2 inhibition of platelet aggregation.
A Eldor et al.
Thrombosis research, 16(5-6), 617-628 (1979-01-01)
Simon Finfer et al.
The New England journal of medicine, 350(22), 2247-2256 (2004-05-28)
It remains uncertain whether the choice of resuscitation fluid for patients in intensive care units (ICUs) affects survival. We conducted a multicenter, randomized, double-blind trial to compare the effect of fluid resuscitation with albumin or saline on mortality in a
Prevention of venous thromboembolism.
G P Clagett et al.
Chest, 108(4 Suppl), 312S-334S (1995-10-01)

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