74023

trans-2-Dodecenoyl-L-carnitine

analytical standard

• 동의어(들): (2R)-3-Carboxy-N,N,N-trimethyl-2-[[(2E)-1-oxo-2-dodecen-1-yl]oxy]-1-propanaminium inner salt, C12:1-Carnitine
• 실험식(Hill 표기법): C₁₉H₃₅NO₄
• CAS Number: 1631992-06-7
• Molecular Weight: 341.49
• UNSPSC 코드: 12352200
• NACRES: NB.21

속성

• Grade: analytical standard
• Quality Level: 100
• 분석: ≥93.0% (HPLC)
• 광학 활성: [α]/D -15±2°, c = 0.1 in methanol
• 유통기한: limited shelf life, expiry date on the label
• 응용 분야: clinical testing
• 형식: neat
• 저장 온도: −20°C
• SMILES string: [O-]C(C([H])([H])[C@](OC(/C([H])=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O)([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=O

설명

일반 설명

trans-2-Dodecenoyl-L-carnitine belongs to the class of medium-chain acylcarnitines.[1] Acyl-L-carnitines are mostly produced from L-carnitine, which plays an important role in fatty acid metabolic pathways. It acts as a carrier of long-chain acyl groups from activated fatty acids across the inner mitochondrial membrane into the mitochondrial matrix where they undergo β-oxidation to acetyl CoA to obtain usable energy via the citric acid cycle.

trans-2-Dodecenoyl-L-carnitine, belongs to the class of acylcarnitines. It serves as a specific diagnostic metabolite biomarker, which increases in very-long-chain acyl CoA dehydrogenase (VLCAD) deficiency, determined in biological samples.[2][3]

애플리케이션

trans-2-Dodecenoyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological fluids of horses with atypical myopathy using gas chromatography coupled to mass spectrometry.[4] It may also be used as an analytical standard to quantify the analyte in biological samples of patients with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using high-performance liquid chromatography/tandem quadrupole mass spectrometry (HPLC-TQMS).[5]

trans-2-Dodecenoyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological samples of horses with atypical myopathy using gas chromatography-mass spectrometry (GC−MS).[4] It may also be used as an analytical standard to quantify the analyte in biological samples of patients with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using high-performance liquid chromatography/tandem quadrupole mass spectrometry (HPLC-TQMS).[5]

추천 제품

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안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable