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Merck
모든 사진(1)

주요 문서

33871

Supelco

2-Nitrobenzaldehyde semicarbazone

VETRANAL®, analytical standard

동의어(들):

2-NP-SCA, 4-(2-Nitrobenzylidene)semicarbazide

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About This Item

실험식(Hill 표기법):
C8H8N4O3
CAS Number:
Molecular Weight:
208.17
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

제품 라인

VETRANAL®

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

clinical testing

형식

neat

SMILES string

NC(=O)N\N=C\c1ccccc1[N+]([O-])=O

InChI

1S/C8H8N4O3/c9-8(13)11-10-5-6-3-1-2-4-7(6)12(14)15/h1-5H,(H3,9,11,13)/b10-5+

InChI key

OEOKLBSECDAYSM-BJMVGYQFSA-N

일반 설명

2-Nitrobenzaldehyde semicarbazone is a semicarbazone derivative of 2-Nitrobenzaldehyde.[1]

애플리케이션

2-Nitrobenzaldehyde semicarbazone (2-NBA-SC) may be used as an analytical reference standard for the determination of 2-NBA-SC in:
  • Animal muscle tissues by solid-phase extraction (SPE) and high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) equipped with electrospray ionization (ESI) source and multiple reaction monitoring (MRM) detection.[2]
  • Milk of dairy cows by LC-MS/MS with selected reaction monitoring (SRM) detection.[3]
  • Azodicarbonamide-treated flour samples by isotope dilution liquid chromatography coupled to ESI-LC-MS/MS.[4]
  • Shrimp dosed with nitrofurans by ESI-LC-MS/MS with SRM detection.[5]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

기타 정보

Derivatized standard for the assay of nitrofurans in animal tissue by LC/MS

법적 정보

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

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문서 라이브러리 방문

Liquid chromatography- tandem mass spectrometry for the determination of protein-bound residues in shrimp dosed with nitrofurans.
Chu PS and Lopez MI
Journal of Agricultural and Food Chemistry, 53(23), 8934-8939 (2005)
Determination of the metabolites of nitrofuran antibiotics in animal tissue by high-performance liquid chromatography-tandem mass spectrometry.
Leitner A, et al.
Journal of Chromatography A, 939(1-2), 49-58 (2001)
Microwave-assisted Synthesis and Bioevaluation of Some Semicarbazones.
Jafri L, et al.
Chemical Biology & Drug Design, 79(6), 950-959 (2012)
Determination of nitrofuran residues in milk of dairy cows using liquid chromatography- tandem mass spectrometry.
Chu PS and Lopez MI
Journal of Agricultural and Food Chemistry, 55(6), 2129-2135 (2007)
Adam Becalski et al.
Journal of agricultural and food chemistry, 52(18), 5730-5734 (2004-09-18)
Semicarbazide was previously found in foods that were in contact with rubber gaskets foamed at high temperatures with a blowing agent azodicarbonamide. Because azodicarbonamide is an approved flour additive in certain countries, we set out to ascertain if semicarbazide is

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