186562

Tetrahydrofuran

≥99.9%, anhydrous, contains 250 ppm BHT as inhibitor

• 동의어(들): THF, Butylene oxide, Oxolane, Tetramethylene oxide
• 실험식(Hill 표기법): C₄H₈O
• CAS Number: 109-99-9
• Molecular Weight: 72.11
• Beilstein: 102391
• EC Number: 203-726-8
• MDL number: MFCD00005356
• UNSPSC 코드: 12191501
• PubChem Substance ID: 57647757
• NACRES: NA.21

속성

• product name: Tetrahydrofuran, anhydrous, contains 250 ppm BHT as inhibitor, ≥99.9%
• Grade: anhydrous
• Quality Level: 200
• vapor density: 2.5 (vs air)
• vapor pressure: 114 mmHg ( 15 °C); 143 mmHg ( 20 °C)
• 분석: ≥99.9%
• 형태: liquid
• autoignition temp.: 610 °F
• 포함: 250 ppm BHT as inhibitor
• expl. lim.: 1.8-11.8 %
• 불순물: ≤0.005% peroxides (as H₂O₂); <0.002% water (All units except 100 mL); <0.005% water (100 mL pkg)
• refractive index: n20/D 1.407 (lit.)
• pH: ~7
• bp: 65-67 °C (lit.)
• mp: −108 °C (lit.)
• solubility: H₂O: soluble
• density: 0.889 g/mL at 25 °C (lit.)
• SMILES string: C1CCOC1
• InChI: 1S/C4H8O/c1-2-4-5-3-1/h1-4H2
• InChI key: WYURNTSHIVDZCO-UHFFFAOYSA-N

설명

일반 설명

Tetrahydrofuran (THF) is a saturated cyclic ether mainly used as an organic solvent. On long term storage it forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation. It constitutes the key fragment of various natural products (polyether antibiotics). THF forms double hydrate with hydrogen sulfide, crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies.

애플리케이션

Dry tetrahydrofuran (THF) has been used in the synthesis of dichloro{bis[1,1′,1′′-(phosphinetriyl)tripiperidine]}palladium [(P(NC₅H₁₀)₃)₂Pd(Cl)₂], which is widely used in the Heck reaction as a catalyst. It has been employed in the reaction medium of the Heck cross-coupling reaction of various aryl bromides and olefins.

포장

View returnable container options.

기타 정보

Greener alternatives are available for many THF applications, 2-Methyltetrahydrofuran (414247) and Cyclopentyl methyl ether (675970)

안전성 정보

• 픽토그램: GHS02,GHS08,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H302,H319,H335,H336,H351
• 예방조치 성명서: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• 표적 기관: Central nervous system, Respiratory system
• 보충제 위험성: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point (°F): -6.2 °F - closed cup
• Flash Point (°C): -21.2 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter