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Merck
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주요 문서

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06655

Sigma-Aldrich

(R)-(−)-1-Aminoethylphosphonic acid

≥97.0% (NT)

동의어(들):

L-(−)-1-Aminoethylphosphonic acid, L-Ala(P)

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About This Item

Linear Formula:
CH3CH(NH2)P(O)(OH)2
CAS Number:
60687-36-7
Molecular Weight:
125.06
Beilstein:
4291032
MDL number:
MFCD00066502
UNSPSC 코드:
12352116
PubChem Substance ID:
329748255
NACRES:
NA.22

분석

≥97.0% (NT)

광학 활성

[α]20/D −4.8±0.5°, c = 5% in H2O

저장 온도

2-8°C

SMILES string

C[C@H](N)P(O)(O)=O

InChI

1S/C2H8NO3P/c1-2(3)7(4,5)6/h2H,3H2,1H3,(H2,4,5,6)/t2-/m1/s1

InChI key

UIQSKEDQPSEGAU-UWTATZPHSA-N

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일반 설명

(R)-(-)-1-Aminoethylphosphonic acid is a synthetic analog of L-alanine that shows antibacterial property.

애플리케이션

(R)-(−)-1-Aminoethylphosphonic acid can be used to prepare copper(II) heteroligand complexes, which are employed in the solution equilibrium studies.[1]

기타 정보

Di- to tetrapeptides with this amino acid analogue at the "P-terminal" are bactericides and synergistic potentiators of penicillins and cephalophorins.[2][3][4]

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H315,H319,H335

예방조치 성명서

P261 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves

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시험 성적서(COA)

Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Reaction of Alanine Racemase with 1-Aminoethylphosphonic Acid Forms a Stable External Aldimine
Stamper CGF, et al.
Biochemistry, 37(29), 10438-10445 (1998)
F R Atherton et al.
Antimicrobial agents and chemotherapy, 15(5), 677-683 (1979-05-01)
Peptide mimetics with C-terminal residues simulating natural amino acids have been designed as inhibitors of bacterial cell wall biosynthesis. The phosphonopeptide series consisting of various l and d residues of natural amino acids combined with 1-aminoalkyl (and aryl-alkyl-) phosphonic acid
J G Allen et al.
Antimicrobial agents and chemotherapy, 16(3), 306-313 (1979-09-01)
The metabolism and pharmacokinetics of a synthetic antibacterial phosphonodipeptide, alafosfalin, have been studied in rats, baboons, and human volunteers. The compound was rapidly absorbed from the injection site after subcutaneous and intramuscular administration and gave peak plasma concentrations at 15
Stabilities and coordination modes of α-alaninephosphonic acid in copper (II) heteroligand complexes with ethylenediamine, diethylenetriamine or N, N, N′, N′, N″-pentamethyldiethylene triamine in aqueous solution
Kamecka A, et al.
Journal of Solution Chemistry, 40(6), 1041-1054 (2011)
Phosphonopeptides, a new class of synthetic antibacterial agents.
J G Allen et al.
Nature, 272(5648), 56-58 (1978-03-02)
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