추천 제품
제품명
HOG Human Oligodendroglioma Cell Line, HOG human oligodendroglioma cell line is a useful model to study the role of oligodendrocytes in neurodegenerative diseases.
생물학적 소스
human
기술
cell based assay: suitable
cell culture | mammalian: suitable
일반 설명
HOG is a clonal cell line derived from a surgically removed human oligodendroglioma (HOG) [1]. HOG cells express oligodendrocyte markers including low levels of the 15-kDa form of myelin basic protein (MBP) and high levels of CNPase protein. HOG cells do not express GFAP, a astrocyte marker and were found to have minimal levels of glutamine synthetase activity [1] [2] [3]. HOG cells express neurotransmitter receptors such as A2-adenosine, prostaglandin E1 (PGE1) and beta2-adrenergic receptores (beta-ARs) that activate the adenylate cylase signaling pathway [1]. HOG cells also express muscarinic and histamine receptors that are linked to inositol phosphate signaling pathways [1] [4].
세포주 설명
Cancer Cells
애플리케이션
Research Category
Neuroscience
Neuroscience
This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact [email protected].
품질
• Each vial contains ≥ 1X106 viable cells.
• Cells are tested by PCR and are negative for HPV-16, HPV-18, Hepatitis A, C, and HIV-1 & 2 viruses as assessed by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are negative for mycoplasma contamination.
• Each lot of cells is genotyped by STR analysis to verify the unique identity of the cell line.
• Cells are tested by PCR and are negative for HPV-16, HPV-18, Hepatitis A, C, and HIV-1 & 2 viruses as assessed by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are negative for mycoplasma contamination.
• Each lot of cells is genotyped by STR analysis to verify the unique identity of the cell line.
저장 및 안정성
Store in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
면책조항
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Stefania Braidotti et al.
Biomedicines, 11(11) (2023-11-25)
Oligodendroglioma (OG) is a brain tumor that contributes to <1% of brain tumor diagnoses in the pediatric population. Unfortunately, pediatric OG remains without definitive molecular characteristics to aid in diagnosis, and little is known about the tumor microenvironment. Tumor cells'
George H De Vries et al.
Neurochemical research, 35(12), 1978-2000 (2010-12-04)
The importance and essential functions of glial cells in the nervous system are now beginning to be understood and appreciated. Glial cell lines have been instrumental in the elucidation of many of these properties. In this Overview, the origin and
Suixin Liang et al.
Neuropsychiatric disease and treatment, 19, 1625-1631 (2023-07-24)
Moderate therapeutic hypothermia is protective against several cellular stressors. However, the mechanisms behind this protection are not entirely known. In the current investigation, we investigated that therapeutic hypothermia at 33°C administered following peroxide-induced oxidative stress might protect human oligodendroglioma cells
Lynn Vitale-Cross et al.
EBioMedicine, 78, 103981-103981 (2022-04-08)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections result in the temporary loss of smell and taste in about one third of confirmed cases. We used immunohistochemistry to confirm the presence of ACE2, NRP1 and TMPRSS2 in two cranial nerves (IX
Marta Merli et al.
Frontiers in bioengineering and biotechnology, 10, 1032542-1032542 (2023-01-10)
Introduction: In the view of 3D-bioprinting with cell models representative of neural cells, we produced inks to mimic the basic viscoelastic properties of brain tissue. Moving from the concept that rheology provides useful information to predict ink printability, this study
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