Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.
애플리케이션
Research Category Secondary & Control Antibodies
Research Sub Category Whole Immunoglobulin Secondary Antibodies
This Goat anti-Mouse IgG Antibody, Cy3 conjugate is validated for use in IF for the detection of Mouse IgG.
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Roberts, TF; Klein, ME; Kubke, MF; Wild, JM; Mooney, R
American journal of physiology. Renal physiology, 305(10), F1383-F1390 (2013-09-21)
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The nervous system of higher eukaryotes is composed of numerous types of neurons and glia that together orchestrate complex neuronal responses. However, this complex pool of cells typically poses analytical challenges in investigating gene expression profiles and their epigenetic basis