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Merck
모든 사진(5)

문서

ABN44

Sigma-Aldrich

Anti-FGF10 Antibody

from rabbit, purified by affinity chromatography

동의어(들):

Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

rat, mouse, human

종 반응성(상동성에 의해 예측)

rhesus macaque (based on 100% sequence homology)

기술

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... FGF10(2255)

일반 설명

Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor family and plays an essential role in the regulation of cell differentiation, tissue repair, tumor growth, embryonic development, and cell proliferation. Mutations in FGF10 have been associated lacrimo-auriculo-dento-digital syndrome (LADDS) which is a form of ectodermal dysplasia.

면역원

KLH-conjugated linear peptide corresponding to human FGF10.

애플리케이션

Detect FGF10 using this Anti-FGF10 Antibody validated for use in WB, IH(P).
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Western Blot Analysis: 0.5 µg/mL from a representative lot detected FGF10 on 10 µg of mouse embryo tissue lysate.

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected FGF10 in mouse epithelial cells, mouse liver, human brain, and human cerebellum tissues.

품질

Evaluated by Western Blot in A549 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected FGF10 on 10 µg of A549 cell lysate.

표적 설명

~23 kDa observed

물리적 형태

Affinity purified
Purified Rabbit Polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4) and 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
A549 cell lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Shawn Liang et al.
Development (Cambridge, England), 145(2) (2018-01-24)
The developmental program that regulates thyroid progenitor cell proliferation is largely unknown. Here, we show that branching-like morphogenesis is a driving force to attain final size of the embryonic thyroid gland in mice. Sox9, a key factor in branching organ
Nan Wang et al.
Cell proliferation, 55(11), e13315-e13315 (2022-07-20)
Ultraviolet light B (UVB) irradiation can induce skin injury and result in keratinocytes proliferation inhibition. However, the molecular understanding of the repair during UVB-induced cell proliferation inhibition remains poorly understood. The purpose of this study was to explore the role
Roberta Haddad-Tóvolli et al.
American journal of physiology. Endocrinology and metabolism, 324(2), E154-E166 (2023-01-05)
Maternal obesity is an important risk factor for obesity, cardiovascular, and metabolic diseases in the offspring. Studies have shown that it leads to hypothalamic inflammation in the progeny, affecting the function of neurons regulating food intake and energy expenditure. In
Grinu Mathew et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(46), 13156-13161 (2016-11-02)
Deficiency in PTEN (phosphatase and tensin homolog deleted on chromosome 10) is the underlying cause of PTEN hamartoma tumor syndrome and a wide variety of human cancers. In skin epidermis, we have previously identified an autocrine FGF signaling induced by
Thomas Volckaert et al.
Developmental cell, 43(1), 48-59 (2017-10-11)
The lung harbors its basal stem/progenitor cells (BSCs) in the protected environment of the cartilaginous airways. After major lung injuries, BSCs are activated and recruited to sites of injury. Here, we show that during homeostasis, BSCs in cartilaginous airways maintain

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