ABE1025

Anti-Achaete-scute homolog 1 Antibody (ASCL1)

from rabbit, purified by affinity chromatography

• 동의어(들): Achaete-scute homolog 1, ASH-1, hASH1, Class A basic helix-loop-helix protein 46, bHLHa46
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: rat, human
• 기술: immunohistochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NP_004307
• UniProt 수납 번호: P50553
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ASCL1(429)

설명

일반 설명

Achaete-scute homolog 1 (ASCL1), also known as MASH1, ASH1 or HASH1, is a basic helix-loop-helix transcription factor. ASCL1 binds to the E box (5′-CANNTG-3′) which then activates transcription. For efficient DNA binding, dimerization with other BHLH proteins is required. Achaete Scute proteins may also be involved in the determination of neuronal precursors in the central and peripheral nervous systems. It is expressed in fetal brain and is essential for the proper development and the survival of subsets of autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer.

면역원

BCP-conjugated linear peptide corresponding to human Achaete-scute homolog 1 (ASCL1).

애플리케이션

This Anti-Achaete-scute homolog 1 Antibody (ASCL1) is validated for use in Western Blotting and Immunohistochemistry for the detection of Achaete-scute homolog 1 (ASCL1).

Western Blotting Analysis: 2.0 µg/mL from a representative lot detected Achaete-scute homolog 1 (ASCL1) in 5 µg of mouse E13-14 brain lysate and A549 cell lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Achaete-scute homolog 1 (ASCL1) in rat cerebellum, rat cerebral cortex, and rat hippocampus tissue.

품질

Evaluated by Western Blotting using lysate from cells over expressing Achaete-scute homolog 1 (ASCL1).

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Achaete-scute homolog 1 (ASCL1) in 5 µg of lysate from cells over expressing Achaete-scute homolog 1 (ASCL1).

표적 설명

~38 kDa observed

기타 정보

Concentration: Please refer to lot specific datasheet.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable