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Merck
모든 사진(4)

문서

AB4336

Sigma-Aldrich

Anti-SCA-1 Antibody

from rabbit, purified by affinity chromatography

동의어(들):

Lymphocyte antigen 6A-2/6E-1, Ly-6A.2/Ly-6E.1, T-cell-activating protein, Stem cell antigen 1

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

rat, mouse

기술

immunocytochemistry: suitable
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

mouse ... Ly6A(110454)

일반 설명

Stem cell antigen 1 (SCA-1) is a membrane protein belonging to the Ly-6 family of proteins and contains a single UPAR/Ly6 domain. SCA-1 is involved in the activation of T-cells and is thought to have a critical role in the differentiation, proliferation, and survival of a variety of stem cells. Recent studies have indicated SCA-1 to be an ideal marker for the isolation and purification of stem cells for research and further characterization. It is expressed by both progenitor and stem cells from several tissue types including; cardiac, hematopoietic, mammary, muscle, skin and testis.

특이성

No Homology to human was found.
This antibody recognizes SCA-1 at the UPAR/Ly6 domain.

면역원

Epitope: UPAR/Ly6 domain
KLH-conjugated linear peptide corresponding to mouse SCA-1 at the UPAR/Ly6 domain.

애플리케이션

Anti-SCA-1 Antibody is an antibody against SCA-1 for use in WB & IC.
Immunocytochemistry Analysis: A 1:500 dilution from a previous lot detected SCA-1 in rat mesenchymal stem cells.
Research Category
Stem Cell Research
Research Sub Category
Hematopoietic Stem Cells

품질

Evaluated by Western Blot in mouse lung tissue lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected SCA-1 in 10 µg of mouse lung tissue lysate.

표적 설명

~14 kDa observed

물리적 형태

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Mouse lung tissue lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Mehmet H Kural et al.
Cell transplantation, 27(9), 1375-1389 (2018-08-11)
Invasive coronary interventions can fail due to intimal hyperplasia and restenosis. Endothelial cell (EC) seeding to the vessel lumen, accelerating re-endothelialization, or local release of mTOR pathway inhibitors have helped reduce intimal hyperplasia after vessel injury. While animal models are
He Wang et al.
Bioactive materials, 16, 433-450 (2022-04-14)
Small-diameter vascular grafts fabricated from synthetic biodegradable polymers exhibit beneficial mechanical properties but often face poor regenerative potential. Different tissue engineering approaches have been employed to improve tissue regeneration in vascular grafts, but there remains a requirement for a new
Gabriel Haas et al.
Journal of biomedical materials research. Part A, 109(11), 2280-2293 (2021-05-08)
Skeletal muscle is inept in regenerating after traumatic injuries such as volumetric muscle loss (VML) due to significant loss of various cellular and acellular components. Currently, there are no approved therapies for the treatment of muscle tissue following trauma. In
Santosh K Yadav et al.
Cell death & disease, 11(3), 186-186 (2020-03-15)
Providing a conducive microenvironment is critical to increase survival of transplanted stem cells in regenerative therapy. Hyperglycemia promotes stem cell death impairing cardiac regeneration in the diabetic heart. Understanding the molecular mechanisms of high glucose-induced stem cell death is important
Christina Doherty et al.
International journal of molecular sciences, 25(3) (2024-02-10)
Peripheral nerve injury denervates muscle, resulting in muscle paralysis and atrophy. This is reversible if timely muscle reinnervation occurs. With delayed reinnervation, the muscle's reparative ability declines, and muscle-resident fibro-adipogenic progenitor cells (FAPs) proliferate and differentiate, inducing fibro-fatty muscle degradation

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