AB3116

Anti-Bcl-xL Antibody, Phospho-specific

serum, Chemicon^®

• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: serum
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 종 반응성: human
• 제조업체/상표: Chemicon^®
• 기술: western blot: suitable
• NCBI 수납 번호: NM_001191.2; NM_138578.1
• UniProt 수납 번호: Q07817
• 배송 상태: dry ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... BCL2L1(598)

설명

일반 설명

Bcl-XL is one of the anti-apoptotic members of the Bcl-2 family of apoptosis regulators and is overexpressed in many human cancers. Studies by Dr. Haldar and his associates suggest that microtubule damaging drugs like Taxol or 2-methoxyestradiol induce phosphorylation of Bcl-XL at serine 62 by kinases such as Jun and this allows those cells to die by apoptosis.

특이성

AB3116 is specific for the Bcl-xL phosphorylated on serine 62. It does not recognize the unphosphorylated form of the protein.

면역원

Epitope: Phospho-specific

Synthetic phosporylated peptide corresponding to a sequence encompassing serine 62 of human Bcl-xL conjugated to KLH.

애플리케이션

Detect Bcl-xL using this Anti-Bcl-xL Antibody, Phospho-specific validated for use in WB.

Immunoblotting: Recommended dilution is 1:100

Optimal dilutions must be determined by end-user.

Research Category
Apoptosis & Cancer

Research Sub Category
BCL2 & Inhibition

Tumor Markers

물리적 형태

Liquid rabbit serum containing no preservatives.

저장 및 안정성

Maintain at -80°C for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable