8.55051

Biotin NovaTag^® resin

Novabiochem^®

• 동의어(들): N-Biotin-NÆ-Fmoc-ethylenediamine MPB-AM resin
• UNSPSC 코드: 12352209

속성

• 제품 라인: NovaSyn^® TG; Novabiochem^®
• 형태: beads
• 반응 적합성: reaction type: Fmoc solid-phase peptide synthesis
• 제조업체/상표: Novabiochem^®
• 응용 분야: peptide synthesis
• 작용기: amine
• 저장 온도: 15-25°C

설명

일반 설명

Biotin NovaTag resin is an ideal tool for the synthesis of peptides labeled with biotin. As the biotin moiety is incorporated into the linker, its use eliminates the problems associated with biotin-labeling of peptides, namely poor solubility and sluggish coupling kinetics of biotin and its derivatives. Following peptide assembly under standard Fmoc SPPS conditions, cleavage with TFA affords the peptide labeled with biotin. For a recent applications see ^[1,2].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

^[1] M. Carraz, et al. (2009) Chemistry & Biology, 16, 702.
^[2] S. Millward, et al. (2007) Chem. Biol., 2, 625.

결합

Replaces: 04-12-3901

분석 메모

Color (visual): white to light yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.35 - 0.65 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer metrix is copoly (styrene - 1% DVB), 100 - 200 mesh.

법적 정보

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany

NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable