539610

PKC_ζ/ι Pseudosubstrate Inhibitor

The PKC_ζ/ι Pseudosubstrate Inhibitor controls the biological activity of PKC_ζ/ι. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• 동의어(들): PKC_ζ/ι Pseudosubstrate Inhibitor, SIYRRGARRWRKL, Protein Kinase C _ζ/ι Pseudosubstrate Inhibitor, SIYRRGARRWRKL, Protein Kinase C_ζ/ι Pseudosubstrate Inhibitor
• 실험식(Hill 표기법): C₇₆H₁₂₈N₃₀O₁₆
• Molecular Weight: 1718.02
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: lyophilized
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated (hygroscopic)
• solubility: glacial acetic acid: 2 mg/mL; water: 2 mg/mL
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

A selective, reversible, and substrate competitive inhibitor of protein kinase C_ζ and protein kinase C_ι (PKC_ζ/ι) isozymes.

Non-cell-permeable protein kinase C_ζ and protein kinase C_ι pseudosubstrate sequence peptide that can be used as a selective, reversible, and substrate competitive inhibitor PKC_ζ/ι in in vitro kinase assays.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
PKCζ

Product does not compete with ATP.

Reversible: yes

경고

Toxicity: Standard Handling (A)

서열

H-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH

물리적 형태

Supplied as a trifluoroacetate salt.

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Sajan, M.P., et al. 1999. J. Biol. Chem.274, 30495.
Laudanna, C., et al. 1998. J. Biol. Chem.273, 30306.
Standaert, M.L., et al. 1997. J. Biol. Chem.272, 30075.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable