538927

15d-PGJ₂

A metabolite of PGD₂that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected NIH/3T3 cells and for PPARγ response element (PPRE) in CV-1 cells.

• 동의어(들): 15d-PGJ₂, Prostaglandin J₂, 15-Deoxy-Δ ^12,14, PPAR Agonist VII, PPARγ Agonist VI
• 실험식(Hill 표기법): C₂₀H₂₈O₃
• CAS Number: 87893-55-8
• Molecular Weight: 316.43
• MDL number: MFCD00065806
• UNSPSC 코드: 12352211
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: oil
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• solubility: DMSO: 25 mg/mL; ethanol: 25 mg/mL
• 배송 상태: wet ice
• 저장 온도: −20°C
• SMILES string: OC(=O)CCC\C=C/C[C@@H]1\C(=C/C=C/CCCCC)\C(=O)C=C1
• InChI: 1S/C20H28O3/c1-2-3-4-5-6-10-13-18-17(15-16-19(18)21)12-9-7-8-11-14-20(22)23/h6-7,9-10,13,15-17H,2-5,8,11-12,14H2,1H3,(H,22,23)/b9-7-,10-6+,18-13+/t17-/m0/s1
• InChI key: VHRUMKCAEVRUBK-GODQJPCRSA-N

설명

일반 설명

A metabolite of PGD₂ that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected 3T3 cells and for PPARγ response element (PPRE) in CV-1 cells. Competes with thiazolidinediones for PPARγ binding.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
A natural ligand for PPARγ-dependent adipogenesis

Product does not compete with ATP.

Reversible: no

포장

Packaged under inert gas

경고

Toxicity: Harmful (C)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Petrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA96, 4668.
Ricote, M., et al. 1998. Nature 391, 79.
Forman, B.M., et al. 1995. Cell 83, 803.
Kliewer, S.A., et al. 1995. Cell83, 813.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable