524394

4α-Phorbol-12,13-didecanoate

>99% (HPLC), solid, PDD and PMA negative control, Calbiochem^®

• 동의어(들): 4α-Phorbol-12,13-didecanoate, 4αPDD, PKC Activator I, Negative Control
• 실험식(Hill 표기법): C₄₀H₆₄O₈
• CAS Number: 27536-56-7
• Molecular Weight: 672.93
• MDL number: MFCD00036737
• UNSPSC 코드: 12352211
• NACRES: NA.77

속성

• 제품명: 4α-Phorbol-12,13-didecanoate, Inactive on mouse skin as an inflammatory and tumor-promoting agent.
• Quality Level: 100
• 분석: >99% (HPLC)
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• solubility: DMSO: soluble; ethanol: soluble
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: O([C@]21[C@H]([C@H]3[C@@]([C@H]4[C@@](CC(=C3)CO)(C(=O)C(=C4)C)O)([C@@H]([C@H]2OC(=O)CCCCCCCCC)C)O)C1(C)C)C(=O)CCCCCCCCC
• InChI: 1S/C40H64O8/c1-7-9-11-13-15-17-19-21-32(42)47-36-28(4)39(46)30(24-29(26-41)25-38(45)31(39)23-27(3)35(38)44)34-37(5,6)40(34,36)48-33(43)22-20-18-16-14-12-10-8-2/h23-24,28,30-31,34,36,41,45-46H,7-22,25-26H2,1-6H3/t28-,30+,31-,34-,36-,38+,39-,40-/m1/s1
• InChI key: DGOSGFYDFDYMCW-OEFRVDPMSA-N

설명

일반 설명

Inactive on mouse skin as an inflammatory and tumor-promoting agent. Useful as a negative control for Phorbol-12,13-didecanoate (PDD; Cat. No. 524392) and Phorbol-12-myristate-13-acetate (PMA; Cat. No. 524400).

Reported to be inactive on mouse skin as an inflammatory and tumor-promoting agent. Used as a negative control for phorbol-12,13-didecanoate (PDD, Cat. No. 524392) and phorbol-12-myristate-13-acetate (PMA, Cat. No. 524400).

생화학적/생리학적 작용

Cell permeable: no

Primary Target
A negative control for Phorbol-12,13-didecanoate (PDD) and Phorbol-12-myristate-13-acetate (PMA)

Product does not compete with ATP.

Reversible: no

포장

Packaged under inert gas

경고

Toxicity: Highly Toxic (H)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 6 months at -20°C.

기타 정보

Akiguchi, I., et al. 1993. Endocrinology 138, 379.
Clarke, B.L., et al. 1993. Endocrinology132, 1168.
Natarajan, V. and Garcia, J.G. 1993. J. Lab. Clin. Med.121, 337.
Slomiany, B.L., et al. 1992. J. Physiol. Pharmacol.43, 223.

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS06,GHS08,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H300 + H310 + H330,H314,H317,H334,H351
• 예방조치 성명서: P201 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Carc. 2 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable