5.08052

iMDK

≥98% (HPLC), solid, midkine inhibitor, Calbiochem^®

• 동의어(들): Midkine Inhibitor, iMDK, 3-(2-(4-Fluorobenzyl)imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one, 3-(2-(4-Fluorobenzyl)imidazo[2,1-b][1,3]thiazol-6-yl)-2H-chromen-2-one, MDK Expression Inhibitor
• 실험식(Hill 표기법): C₂₁H₁₃FN₂O₂S
• CAS Number: 881970-80-5
• Molecular Weight: 376.40
• MDL number: MFCD07528492
• UNSPSC 코드: 12352200
• PubChem Substance ID: 15991416
• NACRES: NA.77

속성

• 제품명: Midkine Inhibitor, iMDK,
• 분석: ≥98% (HPLC)
• Quality Level: 100
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: off-white
• solubility: DMSO: 5 mg/mL
• 저장 온도: 2-8°C
• SMILES string: C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CN4C=C(SC4=N3)CC5=CC=C(C=C5)F
• InChI key: IWFKQTWYILKFGE-UHFFFAOYSA-N

설명

일반 설명

The midkine inhibitor, iMDK, demonstrates strong antiproliferative and antitumor effects both in vitro and in vivo in non-small-cell lung cancer.[1] It also induces apoptosis of primary effusion lymphoma through G2/M cell cycle arrest.[2]

애플리케이션

Midkine Inhibitor, iMDK may be used to study its anti-cancer activity on primary effusion lymphoma (PEL) in vitro.[2]

생화학적/생리학적 작용

Cell permeable: yes

Primary Target
Midkine

Reversible: yes

포장

Packaged under inert gas

경고

Toxicity: Standard Handling (A)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

기타 정보

Hao, H., et al. 2013. PLoS ONE8, e71093.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable