476475

PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated

The PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• 동의어(들): PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated, Myr-N-RKRTLRRL-OH, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Myr-N-RKRTLRRL-OH, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated
• 실험식(Hill 표기법): C₆₀H₁₁₇N₂₁O₁₁
• Molecular Weight: 1308.71
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 형태: lyophilized solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated
• solubility: water: 5 mg/mL
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-erbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor that inhibits protein kinase C (IC₅₀ = 5 µM) in intact cells.

Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-ErbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor of protein kinase C (IC₅₀ = 5 µM).

생화학적/생리학적 작용

Cell permeable: yes

Primary Target
PKC

Product does not compete with ATP.

Reversible: yes

Target IC₅₀: 5 µM against protein kinase C

포장

Yes

경고

Toxicity: Standard Handling (A)

서열

Myr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH

물리적 형태

Supplied as a trifluoroacetate salt.

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

기타 정보

Ward, N.E., and O’Brian, C.A. 1993. Biochemistry32, 11903.
O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable