440345-M

Lysozyme, Human Neutrophil

Occurs in specific granules of human polymorphonuclear leukocytes and takes part in antibacterial activity of leukocytes.

• 동의어(들): Lysozyme, Human Neutrophil, N-Acetylmuramyl Hydrolase, Muramidase
• CAS Number: 9001-63-2
• 효소 위원회 번호: 3.2.1.17 (BRENDA, IUBMB)
• MDL number: MFCD00131557
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• 분석: ≥95% (SDS-PAGE)
• 형태: lyophilized
• 특이 활성도: ≥30,000 Shugar units/mg protein
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• solubility: aqueous buffer: soluble; water: soluble
• 저장 온도: −20°C
• InChI: 1S/C99H159N37O23/c1-11-50(8)77(132-72(139)46-120-81(145)63(32-33-70(101)137)124-88(152)69-31-21-39-136(69)93(157)68(43-73(140)141)131-84(148)62(29-19-37-116-98(109)110)125-90(154)75(48(4)5)135-91(155)76(49(6)7)133-80(144)57(100)24-16-34-113-95(103)104)92(156)126-60(27-17-35-114-96(105)106)82(146)121-51(9)78(142)129-66(41-54-45-119-59-26-15-13-23-56(54)59)87(151)134-74(47(2)3)89(153)122-52(10)79(143)128-65(40-53-44-118-58-25-14-12-22-55(53)58)85(149)123-61(28-18-36-115-97(107)108)83(147)130-67(42-71(102)138)86(150)127-64(94(158)159)30-20-38-117-99(111)112/h12-15,22-23,25-26,44-45,47-52,57,60-69,74-77,118-119H,11,16-21,24,27-43,46,100H2,1-10H3,(H2,101,137)(H2,102,138)(H,120,145)(H,121,146)(H,122,153)(H,123,149)(H,124,152)(H,125,154)(H,126,156)(H,127,150)(H,128,143)(H,129,142)(H,130,147)(H,131,148)(H,132,139)(H,133,144)(H,134,151)(H,135,155)(H,140,141)(H,158,159)(H4,103,104,113)(H4,105,106,114)(H4,107,108,115)(H4,109,110,116)(H4,111,112,117)/t50-,51-,52-,57-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,74-,75-,76-,77-/m0/s1
• InChI key: ZJCXKXFAOCLSRV-RYLVIXIQSA-N

설명

일반 설명

Native lysozyme from human neutrophils. Occurs in specific granules of human polymorphonuclear leukocytes and takes part in antibacterial activity of leukocytes. Hydrolyzes β1,4 linkages between N-acetylmuramic acid (2-acetamido-2-deoxy-3-O-[1′-carboxymethyl]-glucopyranose) residues in chitin.

Native lysozyme from human neutrophils. Occurs in specific granules of human polymorphonuclear leukocytes and takes part in antibacterial activity of leukocytes. Hydrolyzes β1,4-linkages between N-acetylmuramic acid (2-acetamido-2-deoxy-3-O-[1′-carboxymethyl]-glucopyranose) residues in chitin.

경고

Toxicity: Standard Handling (A)

단위 정의

One Shugar unit is defined as the amount of enzyme that will cause a decrease in absorbance of 0.001 at 450 nm per min due to lysis of Micrococcus lysodeikticus at 37°C, pH 7.0.

물리적 형태

Lyophilized from 100 mM NaCl, 50 mM sodium acetate buffer, pH 6.0.

제조 메모

Prepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

재구성

Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 3 days at 4°C or for up to 1 year at -20°C.

기타 정보

Lollike, K., et al. 1995. Leukemia 9, 206.
Gordon, L.I., et al. 1979. J. Clin. Invest. 64, 226.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable