14-746M-M

Src (1-530) Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells. For use in Kinase Assays.

• UNSPSC 코드: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

속성

• 생물학적 소스: human
• Quality Level: 100
• 재조합: expressed in baculovirus infected Sf21 cells
• 분자량: M_w 61.7 kDa
• 제조업체/상표: Upstate^®
• 기술: activity assay: suitable (kinase)
• GenBank 수납 번호: K03218
• UniProt 수납 번호: P05480 (mouse); P12931; Q9WUD9 (rat)
• 유전자 정보: human ... SRC(6714)

설명

일반 설명

N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells.

Product Source: Expressed by baculovirus in Sf21 insect cells.

The mutant form of Src (Src, 1-530) has been identified in cases of advanced colon cancer. This truncating mutation generates an open active form of Src that has been found to be transforming, tumorigenic and metastasis promoting.

애플리케이션

Research Category
Metabolism

Research Sub Category
Cardiovascular Disease

Metabolic Disorders

생화학적/생리학적 작용

Protein Target: Src

Target Sub-Family: TK

포장

Also available in 10 μg size (cat#14-746) and in bulk (cat# 14-746-K).

물리적 형태

50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution

Ni²⁺/NTA-agarose

저장 및 안정성

6 months at -70°C from date of shipment.

기타 정보

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

법적 정보

GenBank is a registered trademark of United States Department of Health and Human Services

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H317
• 예방조치 성명서: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable