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Merck
모든 사진(1)

주요 문서

1.00496

Sigma-Aldrich

Formaldehyde solution 4%, buffered, pH 6.9

(approx. 10% Formalin solution) for histology

동의어(들):

Formaline solution, Methanal solution, Methyl aldehyde solution

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About This Item

UNSPSC 코드:
41116124
NACRES:
NA.21
bp:
100 °C/1013 hPa
제품 1.00496은(는)귀하의 국가에서 현재 판매되지 않습니다. 고객지원팀으로 연락바랍니다.

Quality Level

양식

liquid

IVD

for in vitro diagnostic use

농도

3.8-4.2% (acidimetric)

색상

colorless

pH

6.7-7.1 ( in H2O)

bp

100 °C/1013 hPa

mp

-92 °C

density

1.017 g/cm3 at 20 °C

응용 분야

diagnostic assay manufacturing
hematology
histology

저장 온도

15-25°C

일반 설명

Formaldehyde (HCOH) is one of the most familiar and effective fixatives. Formaldehyde fixation is suitable for nearly all types of histological tissue, as well as calcified deposits, bone, cartilage, nervous system specimens. The fixation of the histological specimen material of human or animal origin is commonly performed in a 4% or 10% Formaldehyde solution. Chemically, the 4 % Formaldehyde solution equals a 10 % Formalin solution. This Formaldehyde solution 4% is a ready-to-use working solution that is stabilized with phosphate buffer to protect tissue structures. The development of formic acid will be effective prevented. It is an IVD registered and CE certified product and can be applied for diagnostical purposes. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

픽토그램

Exclamation markHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Soham Gupta et al.
Frontiers in immunology, 11, 437-437 (2020-04-01)
The hijacking of cellular function through expression of proteins that interfere with the activity of cellular enzymes and regulatory complexes is a common strategy used by viruses to remodel the cell environment in favor of their own replication and spread.

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관련 콘텐츠

Learn about the criticality of biological tissue staining for research and clinical pathology using standard and special stains and dyes.

표준 및 특수 염색과 염료를 사용하여 연구 및 임상 병리학을 위해 생물학적 조직 염색의 중요성에 대해 알아보십시오.

질문

1–2 / 2 질문  
  1. Is it okay to fix an entire tissue with 4% PFA at 37°C overnight using product 1004960700 without altering its morphology?

    1 답변
    1. The temperature used for standard tissue processing historically has been room temperature. Temperature can affect the rate of fixation, and modern tissue processors may use elevated temperatures to reduce processing time without adverse effects on tissue morphology. Cold fixation is common in electron microscopy when using glutaraldehyde as a fixative.

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  2. Do 4% formaldehyde or 10% formalin solutions contain traces of methanol?

    1 답변
    1. Product 1004960700 and all other formaldehyde or formalin solutions contain methanol to prevent the formaldehyde from reforming as a polymer or escaping as a gas. If a methanol-free solution is required, paraformaldehyde powders or crystals can be purchased and prepared into methanol-free solutions, although these solutions are unstable and should be prepared fresh daily or kept for only short periods of time.

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