1.00164

Boric acid

cryst., EMPROVE^® API, Ph. Eur., BP, NF

• 동의어(들): Orthoboric acid, Trihydroxidoboron
• Linear Formula: H₃BO₃
• CAS Number: 10043-35-3
• Molecular Weight: 61.83
• MDL number: MFCD00011337
• UNSPSC 코드: 12352106
• EC 인덱스 번호: 233-139-2

속성

• Agency: BP; NF; Ph. Eur.
• Quality Level: 600
• vapor pressure: 2.6 mmHg ( 20 °C)
• 제품 라인: EMPROVE^® API
• 분석: 99.5-100.5% (alkalimetric)
• 양식: solid
• 효능: 2660 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• pH: 3.8-4.8 (20 °C, 33 g/L in H₂O)
• mp: 160 °C (dec.) (lit.)
• solubility: 49.2 g/L
• density: 1.489 g/cm³ at 23 °C
• 벌크 밀도: 400‑600 kg/m³
• 음이온 미량물: sulfate (SO₄^2-): ≤0.04%
• 양이온 미량물: As: ≤0.0001%; heavy metals (as Pb): ≤0.0015%
• 응용 분야: liquid formulation; ophthalmics; parenterals; pharmaceutical; semi-solid formulation
• 저장 온도: 2-25°C
• SMILES string: OB(O)O
• InChI: 1S/BH3O3/c2-1(3)4/h2-4H
• InChI key: KGBXLFKZBHKPEV-UHFFFAOYSA-N

설명

일반 설명

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

애플리케이션

Boric acid as an active ingredient is used in ophthalmic drugs, as antiseptic for cuts and burns, as well as antibacterial for dermatological treatments such as acne and athlete foot. Boric acid Emprove^® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

법적 정보

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H360FD
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable