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Merck
모든 사진(1)

문서

N-003

Supelco

Norcocaine hydrochloride solution

1.0 mg/mL in acetonitrile (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

실험식(Hill 표기법):
C16H19NO4 · HCl
CAS Number:
Molecular Weight:
325.79
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material

형태

liquid

특징

Snap-N-Spike®/Snap-N-Shoot®

포장

ampule of 1 mL

제조업체/상표

Cerilliant®

농도

1.0 mg/mL in acetonitrile (as free base)

기술

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

응용 분야

forensics and toxicology

형식

single component solution

저장 온도

−20°C

SMILES string

Cl.COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1OC(=O)c3ccccc3)N2

InChI

1S/C16H19NO4.ClH/c1-20-16(19)14-12-8-7-11(17-12)9-13(14)21-15(18)10-5-3-2-4-6-10;/h2-6,11-14,17H,7-9H2,1H3;1H/t11-,12+,13-,14+;/m0./s1

InChI key

RIPPXFWUYXTRNJ-BHARVXRSSA-N

일반 설명

Norcocaine is a primary urinary metabolite of the popular recreation drug cocaine. Cocaine is a central nervous system stimulant with appetite suppressant and topical anesthetic properties. This certified solution standard is applicable for use in urine drug testing, clinical toxicology or forensic toxicology applications by GC/MS or LC/MS.

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

FlameExclamation mark

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

35.6 °F - closed cup

Flash Point (°C)

2 °C - closed cup


시험 성적서(COA)

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문서 라이브러리 방문

Maria João Valente et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(30), 3083-3088 (2010-10-23)
Acute renal failure is a common finding in cocaine abusers. While cocaine metabolism may contribute to its nephrotoxic mechanisms, its pharmacokinetics in kidney cells is hitherto to be clarified. Primary cultures of human proximal tubular cells (HPTCs) provide a well-characterized
Kathleen M Kantak
Expert opinion on pharmacotherapy, 4(2), 213-218 (2003-02-04)
The past decade has seen the development of several vaccines against illicit-drugs. These include vaccines for producing antibodies against cocaine, heroin, methamphetamine and nicotine. The present focus is on anti-cocaine vaccines, as more research has been conducted with these vaccines
L Sun et al.
Drug metabolism and disposition: the biological fate of chemicals, 29(9), 1183-1189 (2001-08-15)
To accurately assess the mechanism of involvement of the active metabolite norcocaine in the effects of oral cocaine, it is essential to determine the rate and extent of the formation of norcocaine. Although this study was designed specifically for this
Christine Moore et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 859(2), 208-212 (2007-10-24)
A quantitative analytical procedure for the determination of cocaine, benzoylecgonine and cocaethylene and norcocaine in hair has been developed and validated. The hair samples were washed, incubated, and any drugs present were quantified using mixed mode solid-phase extraction and liquid
C W Schindler et al.
European journal of pharmacology, 431(1), 53-59 (2001-11-22)
The effects of cocaine and the cocaine metabolites norcocaine, ecgonine methyl ester, benzoylecgonine and cocaethylene were evaluated in conscious squirrel monkeys for their effects on blood pressure and heart rate. Norcocaine, ecgonine methyl ester and benzoylecgonine are produced in vivo

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