Mitragynine, commonly known as Kratom, is the most abundant alkaloid in the plant Mitragynine speciosa. Sold over the internet as herbal plant extracts, Kratom is noted for its psychoactive, stimulant, and sedative effects depending on the dosage level. According to DEA′s Drugs and Chemicals of Concern page, mitragynine use can lead to addiction with adverse effects ranging from anorexia and weight loss to hallucinations and delusion.
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Journal of forensic sciences, 58 Suppl 1, S278-S279 (2012-10-23)
A 17-year-old white man who showed no obvious signs of trauma was found unresponsive in bed and was pronounced dead at the scene. The decedent had a documented history of heroin abuse and chronic back pain and reportedly self-medicated with
[Krypton--new, deadly Internet drug. Since October 2009 have nine young persons died in Sweden].
Journal of analytical toxicology, 35(4), 242-247 (2011-04-26)
The leaves of Kratom, a medicinal plant in Southeast Asia, have been used as an herbal drug for a long time. At least one of the alkaloids present in Kratom, mitragynine, is a mu-receptor agonist. Both Kratom and an additional
Mitragynine is a pharmacologically-active terpenoid indole alkaloid found in Mitragyna speciosa leaves. Treatment with methyl jasmonate (10 μM) for 24 h and yeast extract (0.1 mg/ml) for 12 h were the optimum conditions of elicitation of mitragynine accumulation in a
Journal of addiction medicine, 5(4), 300-301 (2011-08-06)
Here we present a case of a coincidence of addiction to "Kratom" (botanically known as Mitragyna speciosa Korth) and developed severe primary hypothyroidism. We are discussing a possibility that high dose of indole alkaloid mitragynine (the major alkaloid identified from
