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Merck
모든 사진(1)

주요 문서

E-006

Supelco

EDDP perchlorate

ampule of 10 mg, certified reference material, Cerilliant®

동의어(들):

EDDP perchlorate, 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine perchlorate

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About This Item

실험식(Hill 표기법):
C20H23N · HClO4
CAS Number:
Molecular Weight:
377.86
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24
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Grade

certified reference material

양식

solid

특징

Snap-N-Spike®/Snap-N-Shoot®

포장

ampule of 10 mg

제조업체/상표

Cerilliant®

약물 제어

regulated under CDSA - not available from Sigma-Aldrich Canada

기술

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

응용 분야

forensics and toxicology

형식

neat

저장 온도

−20°C

일반 설명

A Certified Reference Material of the major urinary metabolite of methadone. Methadone, sold under various trade names such as Symoron, Amidone or Methadose®, is a synthetic opioid used medically as an analgesic and as a maintenance anti-addictive for use in patients with opioid dependency. Suitable uses for this reference standard include as starting material in preparation of calibrators and controls for LC/MS or GC/MS methods in methadone testing for applications in clinical toxicology or forensic analysis.

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Methadose is a registered trademark of Mallinckrodt Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

관련 제품

제품 번호
설명
가격

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 3 Oral - STOT SE 3

표적 기관

Central nervous system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Matthias Gosselin et al.
Forensic science international, 209(1-3), 154-159 (2011-02-16)
This paper describes a sensitive UPLC-MS/MS method for quantification of methadone and 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) in single empty puparial case of Lucilia sericata. Larvae were reared on substrates spiked with different concentrations of methadone (0-4 μg/g). Methadone was quantified in puparia
Ana de Castro et al.
Clinical chemistry, 57(3), 449-458 (2011-01-20)
Few investigations have used placenta as an alternative matrix to detect in utero drug exposure, despite its availability at the time of birth and the large amount of sample. Methadone-maintained opioid-dependent pregnant women provide a unique opportunity to examine the
Ana de Castro et al.
Therapeutic drug monitoring, 33(4), 443-452 (2011-07-12)
The purpose was to explore methadone and 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) umbilical cord disposition, correlate with maternal methadone dose and neonatal outcomes, and evaluate the window of drug detection in umbilical cord of in utero illicit drug exposure. Subjects comprised 19 opioid-dependent
Edijs Leimanis et al.
Journal of analytical toxicology, 36(4), 239-249 (2012-04-19)
Methadone is used to treat moderate to severe pain in patients not responsive to non-narcotic analgesics and for maintenance treatment of opioid addiction. Methadone is primarily metabolized by N-demethylation to an inactive metabolite 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidene (EDDP) by CYP3A4 and CYP2B6. Establishing
M Rosa Boleda et al.
Chemosphere, 84(11), 1601-1607 (2011-06-15)
A total of seventy samples of drinking water were tested for non-controlled and illicit drugs. Of these, 43 were from Spanish cities, 15 from seven other European countries, three from Japan and nine from seven different Latin American countries. The

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