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Merck
모든 사진(1)

주요 문서

LM2001

Avanti

Sphinganine (d17:0)

heptadecasphinganine, ethanol solution

동의어(들):

(2S,3R)-2-aminoheptadecane-1,3-diol, C17 Sphinganine

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About This Item

실험식(Hill 표기법):
C17H37NO2
CAS Number:
Molecular Weight:
287.48
UNSPSC 코드:
12352211
NACRES:
NA.25

양식

ethanol solution

포장

pkg of 1 × 1 mL (LM2001-1EA)

제조업체/상표

Avanti Research - A Croda Brand LM2001

농도

~10 μg/mL (Refer to C of A for lot specific concentration.)

배송 상태

dry ice

저장 온도

−20°C

SMILES string

OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCC

InChI

1S/C17H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)16(18)15-19/h16-17,19-20H,2-15,18H2,1H3/t16-,17+/m0/s1

InChI key

KFQUQCFJDMSIJF-DLBZAZTESA-N

일반 설명

Sphinganine, also known as dihydrosphingosine is a sphingoid base precursor of ceramide.[1][2]

애플리케이션

Sphinganine (d17:0) has been used as a constituent of the internal standard mixture in mass spectrometry.[3]

생화학적/생리학적 작용

Sphinganine (SPA) is involved in sphingolipid biosynthesis pathway. It is free from the double bond.[4] SPA has an ability to inhibit the activity of protein kinase c. SPA accumulation enables fumonisin B1 to stimulate apoptosis.[5]
Sphinganine plays a vital role in cell regulation, cell growth modulation and signal transmission, functioning as an inhibitor of protein kinase C.[2] It inhibits the low-density lipoprotein-induced esterification of cholesterol by the blockage of post-lysosomal cholesterol transport.[6] Sphinganine is useful as a biomarker for studying microbial diversity.[7]

포장

2 mL Amber Glass Sealed Ampule (LM2001-1EA)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

FlameExclamation mark

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point (°F)

55.4 °F - closed cup

Flash Point (°C)

13.0 °C - closed cup


가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2
Takabe, et al.
Test, 285(14) (2010)
A stereoselective synthesis of dihydrosphingosine
Fernandes RA and Kumar P
European Journal of Organic Chemistry, 2000(20), 3447-3449 (2000)
Urinary metabolomic profiling in Zucker diabetic fatty rats with type 2 diabetes mellitus treated with glimepiride, metformin, and their combination
Dong Y, et al.
Molecules (Basel), 21(11), 1446-1446 (2016)
Persistence and reversibility of the elevation in free sphingoid bases induced by fumonisin inhibition of ceramide synthase
Enongene EN, et al.
Toxicological Sciences, 67(2), 173-181 (2002)
Quantification of sphingosine and sphinganine from crude lipid extracts by HPLC electrospray ionization tandem mass spectrometry
Lieser B, et al.
Journal of Lipid Research, 44(11), 2209-2216 (2003)

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