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Merck
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주요 문서

870604P

Avanti

oxPAPC

Avanti Research™ - A Croda Brand 870604P, powder

동의어(들):

oxPAPC, Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine

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크기 선택

500 μG
₩309,271

₩309,271

예상 입고일2025년 2월 17일세부사항

벌크 견적 요청
모든 사진(1)

크기 선택

보기 변경
500 μG
₩309,271

About This Item

UNSPSC 코드:
12352211
NACRES:
NA.25

₩309,271

예상 입고일2025년 2월 17일세부사항

벌크 견적 요청

양식

powder

포장

pkg of 1 × 500 μg (870604P-500ug)

제조업체/상표

Avanti Research™ - A Croda Brand 870604P

지질 유형

phosphoglycerides
phospholipids

배송 상태

dry ice

저장 온도

−20°C

일반 설명

Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) is a mixture of oxidized phospholipid[1] and a bioactive constituent of oxidized low-density lipoproteins (LDLs).[2]

애플리케이션

Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) is suitable for use to stimulate murine alveolar macrophages in vitro.[3] It is also suitable for use to study its effects on human aortic endothelial cell metabolic reprogramming.[1]

생화학적/생리학적 작용

Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) show barrier-protective effects on human pulmonary endothelial monolayers.[2] This lipid induce endothelial dysfunction by stimulating both pro- and anti-inflammatory pathways.[1] OxPAPC is highly accumulated in atherosclerotic lesions and other sites of chronic inflammation.[4]

포장

5 mL Clear Glass Sealed Ampule (870604P-500ug)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Arid5a-deficient mice are highly resistant to bleomycin-induced lung injury
Dubey PK, et al.
International Immunology, 29(2), 79-85 (2017)
Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC
Li R, et al.
Circulation Research, 98(5), 642-650 (2006)
Signal transduction pathways activated in human pulmonary endothelial cells by OxPAPC, a bioactive component of oxidized lipoproteins
Birukov KG, et al.
Microvascular Research, 67(1), 18-28 (2004)
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells.
Hitzel J, et al.
Nature Communications, 9(1), 2292-2292 (2018)
Corinne M Spickett et al.
Free radical biology & medicine, 51(12), 2133-2149 (2011-10-11)
Phospholipids are complex and varied biomolecules that are susceptible to lipid peroxidation after attack by free radicals or electrophilic oxidants and can yield a large number of different oxidation products. There are many available methods for detecting phospholipid oxidation products

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