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840030P

Avanti

06:0 PS

1,2-dihexanoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

동의어(들):

PS(6:0/6:0)

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크기 선택

10 MG
₩376,058
25 MG
₩626,357

₩376,058

구입 가능 여부는 고객센터에 문의하십시오.
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모든 사진(2)

크기 선택

보기 변경
10 MG
₩376,058
25 MG
₩626,357

About This Item

실험식(Hill 표기법):
C18H33NO10PNa
CAS Number:
321862-85-5
Molecular Weight:
477.42
UNSPSC 코드:
51191904
NACRES:
NA.25

₩376,058

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 10 mg (840030P-10mg)
pkg of 1 × 25 mg (840030P-25mg)

제조업체/상표

Avanti Research™ - A Croda Brand 840030P

지질 유형

phospholipids
cardiolipins

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O.[Na+]

InChI

1S/C18H34NO10P.Na/c1-3-5-7-9-16(20)26-11-14(29-17(21)10-8-6-4-2)12-27-30(24,25)28-13-15(19)18(22)23;/h14-15H,3-13,19H2,1-2H3,(H,22,23)(H,24,25);/q;+1/p-1/t14-,15+;/m1./s1

InChI key

OPDYVXCKOQKYDZ-LIOBNPLQSA-M

일반 설명

Phosphatidylserine (PS) is an acidic phospholipid.[1] Approximately 15–33 mol% of PS is present in the inner leaflet of the plasma membrane.[2]

애플리케이션

06:0 PS may be used to study its effect on α-syn (α-synuclein) oligomerization by DA (dopamine)[3] and as a phospholipid substrate to determine the kinetic parameters for phospholipase C by chromogenic assay.[4] It has also been used in the preparation of phospholipid vesicles.[5]

생화학적/생리학적 작용

Phosphatidylserine (PS) participates in several signaling pathways.[1] This membrane phospholipid controls the Akt (protein kinase B) phosphorylation process.[6]

포장

5 mL Clear Glass Sealed Ampule (840030P-10mg)
5 mL Clear Glass Sealed Ampule (840030P-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

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시험 성적서(COA)

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문서 라이브러리 방문

Akt-GSK3 beta Pro-survival Signaling Pathway in Cerebral Ischemic Injury
Primer on Kidney Diseases, Volume 953, 269-272 (2017)
Mingquan Guo et al.
Journal of molecular neuroscience : MN, 33(1), 67-73 (2007-09-29)
Phosphatidylserine (PS), the major acidic phospholipid class in eukaryotic biomembranes, plays an important role in various signaling pathways. We have previously demonstrated that docosahexaenoic acid (DHA, 22:6n-3) positively modulates PS biosynthesis and accumulation in neuronal cells, promoting survival. In this
Analysis of complex lipidomes
Medical Applications of Mass Spectrometry, 223-249 (2008)
Chi L L Pham et al.
Bioscience reports, 33(5) (2013-09-27)
The deposition of α-syn (α-synuclein) as amyloid fibrils and the selective loss of DA (dopamine) containing neurons in the substantia nigra are two key features of PD (Parkinson's disease). α-syn is a natively unfolded protein and adopts an α-helical conformation
Carolina Varela Chavez et al.
Cellular microbiology, 17(10), 1477-1493 (2015-04-18)
Clostridium sordellii lethal toxin (TcsL) is a potent virulence factor belonging to the large clostridial glucosylating toxin family. TcsL enters target cells via receptor-mediated endocytosis and delivers the N-terminal catalytic domain (TcsL-cat) into the cytosol upon an autoproteolytic process. TcsL-cat
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문서

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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