추천 제품
분석
>99% (TLC)
형태
powder
포장
pkg of 1 × 100 μg (810314P-100ug)
pkg of 1 × 250 μg (810314P-250ug)
pkg of 1 × 50 μg (810314P-50ug)
제조업체/상표
Avanti Research™ - A Croda Brand 810314P
배송 상태
dry ice
저장 온도
−20°C
일반 설명
Phytosphingosine (PHS) is one of the important constituent of phytoceramides. This sphingoid has a hydroxyl group at C-4 of the sphingoid long-chain base. PHS is a component of mammalian epidermis and is widely distributed in fungi and plants. Nitrobenzoxadiazole/7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) is a fluorescent conjugate.
애플리케이션
NBD Phytosphingosine has been used as a substrate in ceramide synthase assays.
생화학적/생리학적 작용
Phytosphingosine (PHS) is capable of activating G-protein coupled receptor 120 (GPR120). Treating cultured keratinocytes (KC) with PHS can enhance the content of ceramide NP. It plays as key role in epidermal differentiation and also possesses anti-inflammatory and antimicrobial activities.
포장
5 mL Amber Glass Screw Cap Vial (810314P-100ug)
5 mL Amber Glass Screw Cap Vial (810314P-250ug)
5 mL Amber Glass Screw Cap Vial (810314P-50ug)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Phytosphingosine is a novel activator of GPR120
Test, 164(1), 27-32 (2018)
The role of ceramide synthases in the pathogenicity of Cryptococcus neoformans
Testing, 22(6), 1392-1400 (2018)
Phytosphingosine Increases Biosynthesis of Phytoceramide by Uniquely Stimulating the Expression of Dihydroceramide C4-desaturase (DES2) in Cultured Human Keratinocytes
Lipids, 53(9), 909-918 (2018)
Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammatory epidermal hyperplasia in hairless mouse skin
Molecular Medicine, 12(1), 17-24 (2006)
Phytosphingosine enhances moisture level in human skin barrier through stimulation of the filaggrin biosynthesis and degradation leading to NMF formation
Archives of Dermatological Research, 309(10), 795-803 (2017)
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