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Merck
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주요 문서

141101C

Avanti

Brain Extract Polar

Avanti Research - A Croda Brand

동의어(들):

Brain Polar Lipid Extract (Porcine)

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크기 선택

100 MG
₩314,346
500 MG
₩967,498

₩314,346


출고 가능일2025년 4월 21일세부사항


벌크 견적 요청

크기 선택

보기 변경
100 MG
₩314,346
500 MG
₩967,498

About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25

₩314,346


출고 가능일2025년 4월 21일세부사항


벌크 견적 요청

양식

chloroform solution

포장

pkg of 1 × 4 mL (141101C-100mg)
pkg of 5 × 4 mL (141101C-500mg)

제조업체/상표

Avanti Research - A Croda Brand

농도

25 mg/mL (141101C-100mg)
25 mg/mL (141101C-500mg)

지질 유형

lipid extracts

배송 상태

dry ice

저장 온도

−20°C

일반 설명

Brain Extract Polar comprises phosphatidylethanolamine as major lipid component. It also contains phosphatidylserine and phosphatidylcholine. The minor components include the phosphatidic acid and phosphatidylinositol.
Brain Polar Lipid Extract is derived from the total lipid extract by precipitation with acetone followed by extraction of the acetone insoluble material with diethyl ether.

애플리케이션

Brain Extract Polar has been used as an artificial membrane solution component for permeability studies.[1] It may be used for coating donor plate during parallel artificial membrane permeability assay (PAMPA) to study blood-brain barrier penetration.[2] It may be used in liposome preparation for dynamin self-assembly assay.[3]

생화학적/생리학적 작용

Brain lipid, especially the polar fraction plays a key role in the inhibition of prion seeded amyloid formation.[4] Lipid extracts from the mammalian tissues like brain, kidney and liver are used in generating model membranes for mimicking real membranes.[5]

포장

5 mL Clear Glass Sealed Ampule (141101C-100mg)
5 mL Clear Glass Sealed Ampule (141101C-500mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

표적 기관

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point (°F)

does not flash

Flash Point (°C)

does not flash


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시험 성적서(COA)

Lot/Batch Number

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Prediction of blood-brain barrier permeation of alpha-adrenergic and imidazoline receptor ligands using PAMPA technique and quantitative-structure permeability relationship analysis
Vucicevic J, et al.
European Journal of Pharmaceutical Sciences, 68(10), 94-105 (2015)
Irene Paterniti et al.
PloS one, 6(1), e15937-e15937 (2011-02-08)
Primary traumatic mechanical injury to the spinal cord (SCI) causes the death of a number of neurons that to date can neither be recovered nor regenerated. During the last years our group has been involved in the design, synthesis and
Laura Campello et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 54(1), 142-159 (2020-02-07)
It is well established that oxidative stress and inflammation are common pathogenic features of retinal degenerative diseases. ITH12674 is a novel compound that induces the transcription factor Nrf2; in so doing, the molecule exhibits anti-inflammatory, and antioxidant properties, and affords
Kalirin12 interacts with dynamin
Xin X, et al.
BMC Neuroscience, 10(1), 61-61 (2009)
Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors
Chierrito TPC, et al.
European Journal of Medicinal Chemistry, 145(10), 431-444 (2018)

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