H54409

trans-4-Hydroxy-L-proline

≥99%, for peptide synthesis

• 동의어(들): (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, Hyp
• 실험식(Hill 표기법): C₅H₉NO₃
• CAS Number: 51-35-4
• Molecular Weight: 131.13
• Beilstein: 81441
• EC Number: 200-091-9
• MDL number: MFCD00064320
• UNSPSC 코드: 12352209
• PubChem Substance ID: 24895692
• NACRES: NA.22

속성

• 제품명: trans-4-Hydroxy-L-proline, ≥99%
• Quality Level: 200
• 분석: ≥99%
• 양식: crystalline powder
• 광학 활성: [α]25/D −75.6°, c = 1 in H₂O
• 반응 적합성: reaction type: solution phase peptide synthesis
• 색상: white to off-white
• mp: 273 °C (dec.) (lit.)
• 응용 분야: peptide synthesis
• SMILES string: O[C@H]1CN[C@@H](C1)C(O)=O
• InChI: 1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
• InChI key: PMMYEEVYMWASQN-DMTCNVIQSA-N

설명

일반 설명

Trans-4-hydroxy-L-proline is an isomer of hydroxyproline used as a chiral building block in the production of many pharmaceuticals like neuroexcitatory kainoids.[1]

애플리케이션

Versatile reagent for the synthesis of neuroexcitatory kainoids[2] and antifungal echinocandins.[3] Also employed in the synthesis of chiral ligands for enantioselective ethylation of aldehydes.[4]

기타 정보

Natural constituent of animal structural proteins such as collagen and elastin.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)