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Merck
모든 사진(1)

주요 문서

554324

Sigma-Aldrich

Phenylacetyl disulfide

96%

동의어(들):

Bis(phenylacetyl) disulfide, Di(phenylacetyl) disulfide

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크기 선택

25 G
₩135,198

₩135,198


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25 G
₩135,198

About This Item

Linear Formula:
(C6H5CH2COS)2
CAS Number:
Molecular Weight:
302.41
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

₩135,198


구입 가능 여부는 고객센터에 문의하십시오.

벌크 견적 요청

Quality Level

분석

96%

양식

solid

mp

59-63 °C (lit.)

작용기

disulfide
phenyl

SMILES string

O=C(Cc1ccccc1)SSC(=O)Cc2ccccc2

InChI

1S/C16H14O2S2/c17-15(11-13-7-3-1-4-8-13)19-20-16(18)12-14-9-5-2-6-10-14/h1-10H,11-12H2

InChI key

IXGZXXBJSZISOO-UHFFFAOYSA-N

일반 설명

Phenylacetyl disulphide serves as a sulfurization reagent during the preparation of phosphates.[1]Phenyl acetyl disulfide can be synthesized by the reaction of phenyl benzenethiolsulfonate with thioacetic acid in the presence of triethylamine.[2]

애플리케이션

Phenylacetyl disulfide (PADS) may be used as a sulphur transfer agent during the synthesis of phosphorothioate oligodeoxyribonucleotides.[3][4][5][6]

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

이미 열람한 고객

A study on the use of phenylacetyl disulfide in the solid-phase synthesis of oligodeoxynucleoside phosphorothioates.
Roelen HCPF, et al.
J. R. Neth. Chem. Soc., 110(7-8), 325-331 (1991)
"Organic disulfides and related substances. XXIII. Unsymmetrical carbonyl disulfides and cognate compounds"
Fiel L and Buckman DJ
The Journal of Organic Chemistry, 32(11), 3467-3470 (1967)
Synthesis of antisense oligonucleotides: Replacement of 3H-1, 2-benzodithiol-3-one 1, 1-dioxide (Beaucage reagent) with phenylacetyl disulfide (PADS) as efficient sulfurization reagent: From bench to bulk manufacture of active pharmaceutical ingredient.
Cheruvallath ZS, et al.
Organic Process Research & Development, 4(3), 199-204 (2000)
Andreas Aemissegger et al.
Tetrahedron, 63(27), 6185-6190 (2007-07-02)
The synthesis of 1-(2-nitrophenylethyl) caged O-phosphorothioylserine, -threonine and -tyrosine derivatives is reported. These amino acid building blocks can be directly incorporated into peptides by Fmoc-based solid phase synthesis as their pentafluorophenyl esters or as symmetric anhydrides. Upon irradiation with UV
Honglu Zhang et al.
Journal of the American Chemical Society, 128(51), 16464-16465 (2006-12-21)
The activation of phosphatidylinositol 3-kinase (PI 3-K) and subsequent production of PtdIns(3,4,5)P3 launches a signal transduction cascade that impinges on a plethora of downstream effects on cell physiology. Control of PI 3-K and PtdIns(3,4,5)P3 levels is an important therapeutic target

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