511188

Methyl indole-5-carboxylate

99%

• 동의어(들): Indole-5-carboxylic acid, methyl ester
• 실험식(Hill 표기법): C₁₀H₉NO₂
• CAS Number: 1011-65-0
• Molecular Weight: 175.18
• MDL number: MFCD00153023
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24873426
• NACRES: NA.22

속성

• 분석: 99%
• mp: 126-128 °C (lit.)
• 작용기: ester
• SMILES string: COC(=O)c1ccc2[nH]ccc2c1
• InChI: 1S/C10H9NO2/c1-13-10(12)8-2-3-9-7(6-8)4-5-11-9/h2-6,11H,1H3
• InChI key: DRYBMFJLYYEOBZ-UHFFFAOYSA-N

설명

일반 설명

Methyl indole-5-carboxylate (Methyl 1H-indole-5-carboxylate), a substituted 1H-indole, can be prepared by the esterification of indole-5-carboxylic acid.[1] Its efficacy as a substrate for indigoid generation has been assessed.[2]

애플리케이션

Methyl indole-5-carboxylate may be used as a reactant in the following processes:

• biosynthesis of inhibitors of protein kinases[2]
• metal-free Friedel-Crafts alkylation[3]
• preparation of diphenylsulfonium ylides from Martin′s sulfurane[4]
• cross dehydrogenative coupling reactions[5]
• synthesis of indirubin derivatives[6]
• preparation of aminoindolylacetates[7]

Methyl indole-5-carboxylate may be used in the preparation of:

• methyl indoline-5-carboxylate[8]
• 1H-indole-5-carbohydrazide[1]
• dimethyl 1H-indole-3,5-dicarboxylate[9]

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves