479179

(S)-(−)-4-Hydroxy-2-pyrrolidinone

97%

• 동의어(들): (S)-β-Hydroxy-γ-butyrolactam
• 실험식(Hill 표기법): C₄H₇NO₂
• CAS Number: 68108-18-9
• Molecular Weight: 101.10
• Beilstein: 1524192
• MDL number: MFCD00273370
• UNSPSC 코드: 12352005
• PubChem Substance ID: 24871604
• NACRES: NA.22

속성

• 분석: 97%
• 광학 활성: [α]23/D −43°, c = 1 in ethanol
• mp: 156-159 °C (lit.)
• 작용기: hydroxyl
• SMILES string: O[C@@H]1CNC(=O)C1
• InChI: 1S/C4H7NO2/c6-3-1-4(7)5-2-3/h3,6H,1-2H2,(H,5,7)/t3-/m0/s1
• InChI key: IOGISYQVOGVIEU-VKHMYHEASA-N

설명

일반 설명

4-Hydroxy-2-pyrrolidinone is an important building block found in many bioactive compounds like streptopyrrolidine. It can be used as an intermediate in the synthesis of various γ-amino acids (GABA) and substituted 2-pyrrolidinones like cynometrine and cynodine.[1]

애플리케이션

(S)-(−)-4-Hydroxy-2-pyrrolidinone can be used as a starting material in the preparation of:

• Biologically significant pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives.[2]
• Substituted azepanes by reacting with various aldehydes via photochemical [5+2] cycloaddition.[3]

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H302,H318
• 예방조치 성명서: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)