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Merck
모든 사진(2)

주요 문서

456764

Sigma-Aldrich

3-Carboxyphenylboronic acid

≥95%

동의어(들):

μ-Carboxyphenylboronic acid, 3-(Dihydroxyborane)benzoic acid, 3-(Dihydroxyboryl)benzoic acid, 3-Boronobenzoic acid, 3-Carboxybenzeneboronic acid

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About This Item

Linear Formula:
HO2CC6H4B(OH)2
CAS Number:
Molecular Weight:
165.94
MDL number:
UNSPSC 코드:
12352103
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

≥95%

mp

243-247 °C (lit.)

작용기

carboxylic acid

SMILES string

OB(O)c1cccc(c1)C(O)=O

InChI

1S/C7H7BO4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4,11-12H,(H,9,10)

InChI key

DBVFWZMQJQMJCB-UHFFFAOYSA-N

애플리케이션

3-Carboxyphenylboronic acid can be used as a substrate in the preparation of:
  • Biaryl derivatives by reacting with bromoaniline through the Suzuki-Miyaura coupling reaction.
  • Boronic acid-functionalized block copolymer.
  • 1H-Imidazo[1,2-a]quinoxaline derivatives.

기타 정보

Contains varying amounts of anhydride

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

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Calitree, B. D.; Detty, M. R.
Synlett, 89-92 (2010)
Jumin Yang et al.
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Various nanoparticles as drug delivery system provide significant improvements in the cancer treatment. However, their clinical success remains elusive in large part due to their inability to overcome both systemic and tumor tissue barriers. The nanosystems with nanoproperty-transformability (surface, size
Christopher G Barber et al.
Bioorganic & medicinal chemistry letters, 14(12), 3227-3230 (2004-05-20)
A series of 1-isoquinolinylguanidines are shown to be potent inhibitors of uPA with selectivity over tPA and plasmin. Potency is enhanced by the presence of a 4-halo and a 7-aryl substituent, particularly when substituted by a 3-carboxylic acid group. Compound
Heterocycles, 60, 1891-1897 (2003)
New imidazo [1, 2-a] quinoxaline derivatives: synthesis and in vitro activity against human melanoma
Deleuze-Masquefa C, et al.
European Journal of Medicinal Chemistry, 44(9), 3406-3411 (2009)

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