2,2,2-Trifluoroethan(ol-d) is a deuterated compound in which the hydrogen on the –OH group is substituted by deuterium.
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Unspliced XBP1 mRNA encodes XBP1u, the transcriptionally inert variant of the unfolded protein response (UPR) transcription factor XBP1s. XBP1u targets its mRNA-ribosome-nascent-chain-complex to the endoplasmic reticulum (ER) to facilitate UPR activation and prevents overactivation. Yet, its membrane association is controversial.
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