349593

6-Fluoroindole

98%

• 동의어(들): NSC 520436
• 실험식(Hill 표기법): C₈H₆FN
• CAS Number: 399-51-9
• Molecular Weight: 135.14
• Beilstein: 112192
• MDL number: MFCD00056933
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24861689
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 98%
• mp: 72-76 °C (lit.)
• 작용기: fluoro
• SMILES string: Fc1ccc2cc[nH]c2c1
• InChI: 1S/C8H6FN/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5,10H
• InChI key: YYFFEPUCAKVRJX-UHFFFAOYSA-N

설명

일반 설명

6-Fluoroindole is a halogen substituted indole. Experimental ionization potential of 6-fluoroindole has been evaluated.[1] Preparation of 6-fluoroindole via nitration of indoline has been reported.[2]

애플리케이션

6-Fluoroindole may be used as reactant in the preparation of:

• tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators[3]
• antibacterial agents[4]
• antifungal agents[5]
• Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the management of hyperglycemia in diabetes[6]
• potent selective serotonin reuptake inhibitors[7][8]
• inhibitors of HIV-1 attachment[9]

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves