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Merck
모든 사진(1)

문서

230138

Sigma-Aldrich

Oxazole

98%

동의어(들):

1,3-Oxazole, 3-Azafuran

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About This Item

실험식(Hill 표기법):
C3H3NO
CAS Number:
Molecular Weight:
69.06
Beilstein:
103851
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

98%

refractive index

n20/D 1.425 (lit.)

bp

69-70 °C (lit.)

mp

−87-−84 °C (lit.)

density

1.05 g/mL at 25 °C (lit.)

SMILES string

c1cocn1

InChI

1S/C3H3NO/c1-2-5-3-4-1/h1-3H

InChI key

ZCQWOFVYLHDMMC-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Oxazole is the parent molecule for a large class of heterocyclic aromatic compounds. It is a weak base that can be used as an electron-deficient diene in the Diels-Alder cycloaddition reaction. It undergoes nitration, sulfonation, halogenation, Friedel-Crafts alkylation, and acylation.

픽토그램

FlameCorrosion

신호어

Danger

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point (°F)

66.2 °F - closed cup

Flash Point (°C)

19 °C - closed cup

개인 보호 장비

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


시험 성적서(COA)

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문서 라이브러리 방문

Maryna V Kachaeva et al.
Computational biology and chemistry, 74, 294-303 (2018-04-27)
Based on modern literature data about biological activity of E7010 derivatives, a series of new sulfonamides as potential anticancer drugs were rationally designed by QSAR modeling methods Сlassification learning QSAR models to predict the tubulin polymerization inhibition activity of novel
Haseen Ahmad et al.
European journal of medicinal chemistry, 208, 112759-112759 (2020-09-05)
Oxazole derivatives are important medicinal compounds which are inhibitors of various enzymes such as NPP1, NPP2, NPP3, tyrosine kinase, dipeptidyl-peptidase IV, cyclooxygenase-2, and protein tyrosine phosphatase. In this study, an extensive range of new biologically active biphenyl oxazole derivatives was
Systematic scientific study of 1, 3-oxazole derivatives as a useful lead for pharmaceuticals: A review
Joshi S, et al.
The pharma innovation journal, 6, 109-109 (2017)
Lori M Culberson et al.
Physical chemistry chemical physics : PCCP, 16(9), 3964-3972 (2014-01-22)
Bond breaking is a challenging problem in both experimental and theoretical chemistry, due to the transient nature and multi-configurational electronic structure of dissociating molecules. We use anion photodetachment to probe the diradical interactions in the ring-opening reaction of oxazole and
Fengjiao Zhang et al.
Toxicological sciences : an official journal of the Society of Toxicology, 140(1), 118-134 (2014-04-23)
The generation of reactive oxygen species (ROS) has been implicated in the pathogenesis of renal ischemia/reperfusion injury, and many other pathological conditions. DNA strand breaks caused by ROS lead to the activation of poly(ADP-ribose)polymerase-1 (PARP-1), the excessive activation of which

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