์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Merck
๋ชจ๋“  ์‚ฌ์ง„(2)

์ฃผ์š” ๋ฌธ์„œ

159034

Sigma-Aldrich

Acetohydroxamic acid

98%

๋™์˜์–ด(๋“ค):

AHA

๋กœ๊ทธ์ธ์กฐ์ง ๋ฐ ๊ณ„์•ฝ ๊ฐ€๊ฒฉ ๋ณด๊ธฐ

ํฌ๊ธฐ ์„ ํƒ

5 G
โ‚ฉ93,076
10 G
โ‚ฉ140,578
50 G
โ‚ฉ609,000

โ‚ฉ93,076


์˜ˆ์ƒ ์ž…๊ณ ์ผ2025๋…„ 4์›” 21์ผ์„ธ๋ถ€์‚ฌํ•ญ


๋ฒŒํฌ ๊ฒฌ์  ์š”์ฒญ

ํฌ๊ธฐ ์„ ํƒ

๋ณด๊ธฐ ๋ณ€๊ฒฝ
5 G
โ‚ฉ93,076
10 G
โ‚ฉ140,578
50 G
โ‚ฉ609,000

About This Item

Linear Formula:
CH3CONHOH
CAS Number:
Molecular Weight:
75.07
Beilstein:
1739019
EC Number:
MDL number:
UNSPSC ์ฝ”๋“œ:
12352100
PubChem Substance ID:
NACRES:
NA.22

โ‚ฉ93,076


์˜ˆ์ƒ ์ž…๊ณ ์ผ2025๋…„ 4์›” 21์ผ์„ธ๋ถ€์‚ฌํ•ญ


๋ฒŒํฌ ๊ฒฌ์  ์š”์ฒญ

Quality Level

๋ถ„์„

98%

mp

88-90ย ยฐC (lit.)

์ž‘์šฉ๊ธฐ

amine

SMILES string

CC(NO)=O

InChI

1S/C2H5NO2/c1-2(4)3-5/h5H,1H3,(H,3,4)

InChI key

RRUDCFGSUDOHDG-UHFFFAOYSA-N

์œ ์ „์ž ์ •๋ณด

์œ ์‚ฌํ•œ ์ œํ’ˆ์„ ์ฐพ์œผ์‹ญ๋‹ˆ๊นŒ? ๋ฐฉ๋ฌธ ์ œํ’ˆ ๋น„๊ต ์•ˆ๋‚ด

๊ด€๋ จ ์นดํ…Œ๊ณ ๋ฆฌ

์ผ๋ฐ˜ ์„ค๋ช…

Acetohydroxamic acid is a potent inhibitor of bacterial urease activity and reduces urinary ammonia levels.[1] 2-Acetohydroxamic acid loaded floating microspheres forms an efficient drug delivery system for the treatment of Helicobacter pylori.[2]

์• ํ”Œ๋ฆฌ์ผ€์ด์…˜

Acetohydroxamic acid was used:
  • to study the mechanism of complexation of iron (III) with acetohydroxamic acid[3]
  • to study the inhibitory mechanism of lansoprazole and omeprazole on Helicobacter pyloni[4]
  • in urease inhibition studies[5][6]
  • for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile[7]
Used in urease inhibition studies[5][6] and for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile.[7]

ํ”ฝํ† ๊ทธ๋žจ

Health hazard

์‹ ํ˜ธ์–ด

Danger

์œ ํ•ด ๋ฐ ์œ„ํ—˜ ์„ฑ๋ช…์„œ

์˜ˆ๋ฐฉ์กฐ์น˜ ์„ฑ๋ช…์„œ

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

๊ฐœ์ธ ๋ณดํ˜ธ ์žฅ๋น„

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges


๊ฐ€์žฅ ์ตœ์‹  ๋ฒ„์ „ ์ค‘ ํ•˜๋‚˜๋ฅผ ์„ ํƒํ•˜์„ธ์š”:

์‹œํ—˜ ์„ฑ์ ์„œ(COA)

Lot/Batch Number

์ ํ•ฉํ•œ ๋ฒ„์ „์„ ์ฐพ์„ ์ˆ˜ ์—†์œผ์‹ ๊ฐ€์š”?

ํŠน์ • ๋ฒ„์ „์ด ํ•„์š”ํ•œ ๊ฒฝ์šฐ ๋กœํŠธ ๋ฒˆํ˜ธ๋‚˜ ๋ฐฐ์น˜ ๋ฒˆํ˜ธ๋กœ ํŠน์ • ์ธ์ฆ์„œ๋ฅผ ์ฐพ์„ ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค.

์ด ์ œํ’ˆ์„ ์ด๋ฏธ ๊ฐ€์ง€๊ณ  ๊ณ„์‹ญ๋‹ˆ๊นŒ?

๋ฌธ์„œ ๋ผ์ด๋ธŒ๋Ÿฌ๋ฆฌ์—์„œ ์ตœ๊ทผ์— ๊ตฌ๋งคํ•œ ์ œํ’ˆ์— ๋Œ€ํ•œ ๋ฌธ์„œ๋ฅผ ์ฐพ์•„๋ณด์„ธ์š”.

๋ฌธ์„œ ๋ผ์ด๋ธŒ๋Ÿฌ๋ฆฌ ๋ฐฉ๋ฌธ

์ด๋ฏธ ์—ด๋žŒํ•œ ๊ณ ๊ฐ

Slide 1 of 2

1 of 2

Ethyl acetohydroxamate 97%

Sigma-Aldrich

208922

Ethyl acetohydroxamate

Acetamide ~99% (GC)

Sigma-Aldrich

A0500

Acetamide

Journal of the Chemical Society. Perkin Transactions 1, 1001-1001 (1991)
K Nagata et al.
Antimicrobial agents and chemotherapy, 37(4), 769-774 (1993-04-01)
The gastric proton pump inhibitor lansoprazole, its active analog AG-2000, and omeprazole dose dependently inhibited urease activity extracted with distilled water from Helicobacter pylori cells; the 50% inhibitory concentrations were between 3.6 and 9.5 microM, which were more potent than
D P Griffith et al.
The Journal of urology, 140(2), 318-324 (1988-08-01)
Acetohydroxamic acid is known to inhibit bacterial urease activity, thus, reducing urinary ammonia levels. A double-blind placebo-controlled clinical trial of acetohydroxamic acid was conducted at 12 Veterans Administration spinal cord injury units. A total of 210 male spinal cord injury
R B Umamaheshwari et al.
The Journal of pharmacy and pharmacology, 55(12), 1607-1613 (2004-01-24)
This investigation is part of our ongoing effort to develop effective drug delivery systems for the treatment of Helicobacter pylori infection using polycarbonate (PC) floating microspheres as drug carriers. In an effort to augment the anti-H. pylori effect of acetohydroxamic
Chem. Abstr., 116, 124530f-124530f (1992)

์งˆ๋ฌธ

  1. Hello, Could you tell me the percentage of impurities and define specifically which impurities we can find in this reagent ? Thank you,

    1 ๋‹ต๋ณ€
    1. The product impurities are not identified or quantified. Please see the Specification Sheet: https://www.sigmaaldrich.com/specification-sheets/360/076/159034-BULK_______ALDRICH__.pdf

      ๋„์›€์ด ๋˜์—ˆ์Šต๋‹ˆ๊นŒ?

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ํ‰์  ๊ฐ’ ์—†์Œ

ํ™œ์„ฑ ํ•„ํ„ฐ

์ž์‚ฌ์˜ ๊ณผํ•™์žํŒ€์€ ์ƒ๋ช… ๊ณผํ•™, ์žฌ๋ฃŒ ๊ณผํ•™, ํ™”ํ•™ ํ•ฉ์„ฑ, ํฌ๋กœ๋งˆํ† ๊ทธ๋ž˜ํ”ผ, ๋ถ„์„ ๋ฐ ๊ธฐํƒ€ ๋งŽ์€ ์˜์—ญ์„ ํฌํ•จํ•œ ๋ชจ๋“  ๊ณผํ•™ ๋ถ„์•ผ์— ๊ฒฝํ—˜์ด ์žˆ์Šต๋‹ˆ๋‹ค..

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