์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Merck
๋ชจ๋“  ์‚ฌ์ง„(1)

์ฃผ์š” ๋ฌธ์„œ

14501

Sigma-Aldrich

Poly(ethylene glycol) bis(amine)

Mw 2,000, carboxyl reactive, amine

๋™์˜์–ด(๋“ค):

Polyethylene glycol, O,Oโ€ฒ-Bis(2-aminoethyl)polyethylene glycol, Diaminopolyethylene glycol, PEG-diamine, Polyoxyethylene bis(amine)

๋กœ๊ทธ์ธ์กฐ์ง ๋ฐ ๊ณ„์•ฝ ๊ฐ€๊ฒฉ ๋ณด๊ธฐ

ํฌ๊ธฐ ์„ ํƒ

250 MG
โ‚ฉ205,639
1 G
โ‚ฉ627,879

โ‚ฉ205,639


์ถœ๊ณ  ๊ฐ€๋Šฅ์ผ2025๋…„ 4์›” 16์ผ์„ธ๋ถ€์‚ฌํ•ญ


๋ฒŒํฌ ๊ฒฌ์  ์š”์ฒญ

ํฌ๊ธฐ ์„ ํƒ

๋ณด๊ธฐ ๋ณ€๊ฒฝ
250 MG
โ‚ฉ205,639
1 G
โ‚ฉ627,879

About This Item

Linear Formula:
H2N(CH2CH2O)nCH2CH2NH2
CAS Number:
MDL number:
UNSPSC ์ฝ”๋“œ:
12162002
PubChem Substance ID:
NACRES:
NA.23

โ‚ฉ205,639


์ถœ๊ณ  ๊ฐ€๋Šฅ์ผ2025๋…„ 4์›” 16์ผ์„ธ๋ถ€์‚ฌํ•ญ


๋ฒŒํฌ ๊ฒฌ์  ์š”์ฒญ

์ œํ’ˆ๋ช…

Poly(ethylene glycol) bis(amine), Mw 2,000

์–‘์‹

powder

๋ถ„์ž๋Ÿ‰

Mw 2,000

๋ฐ˜์‘ ์ ํ•ฉ์„ฑ

reagent type: cross-linking reagent
reactivity: carboxyl reactive

ฮฉ-๋

amine

ฮฑ-๋

amine

ํด๋ฆฌ๋จธ ๊ตฌ์กฐ

shape: linear
functionality: homobifunctional

์ €์žฅ ์˜จ๋„

โˆ’20ยฐC

SMILES string

NCCOCCOCCN

InChI

1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2

InChI key

IWBOPFCKHIJFMS-UHFFFAOYSA-N

์œ ์‚ฌํ•œ ์ œํ’ˆ์„ ์ฐพ์œผ์‹ญ๋‹ˆ๊นŒ? ๋ฐฉ๋ฌธ ์ œํ’ˆ ๋น„๊ต ์•ˆ๋‚ด

๊ด€๋ จ ์นดํ…Œ๊ณ ๋ฆฌ

์• ํ”Œ๋ฆฌ์ผ€์ด์…˜


  • Polyethylene Glycol Conjugated Polymeric Nanocapsules for Targeted Delivery of Quercetin to Folate-Expressing Cancer Cells in Vitro and in Vivo: Discusses the use of PEG-bis amine for creating polymeric nanocapsules aimed at enhancing targeted drug delivery (RI El-Gogary et al., 2014).

๊ธฐํƒ€ ์ •๋ณด

Polymer for preparing enzyme conjugates soluble in organic solvents[1]; Promising drug carrier[2]

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (ยฐF)

Not applicable

Flash Point (ยฐC)

Not applicable

๊ฐœ์ธ ๋ณดํ˜ธ ์žฅ๋น„

Eyeshields, Gloves


๊ฐ€์žฅ ์ตœ์‹  ๋ฒ„์ „ ์ค‘ ํ•˜๋‚˜๋ฅผ ์„ ํƒํ•˜์„ธ์š”:

์‹œํ—˜ ์„ฑ์ ์„œ(COA)

Lot/Batch Number

์ ํ•ฉํ•œ ๋ฒ„์ „์„ ์ฐพ์„ ์ˆ˜ ์—†์œผ์‹ ๊ฐ€์š”?

ํŠน์ • ๋ฒ„์ „์ด ํ•„์š”ํ•œ ๊ฒฝ์šฐ ๋กœํŠธ ๋ฒˆํ˜ธ๋‚˜ ๋ฐฐ์น˜ ๋ฒˆํ˜ธ๋กœ ํŠน์ • ์ธ์ฆ์„œ๋ฅผ ์ฐพ์„ ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค.

์ด ์ œํ’ˆ์„ ์ด๋ฏธ ๊ฐ€์ง€๊ณ  ๊ณ„์‹ญ๋‹ˆ๊นŒ?

๋ฌธ์„œ ๋ผ์ด๋ธŒ๋Ÿฌ๋ฆฌ์—์„œ ์ตœ๊ทผ์— ๊ตฌ๋งคํ•œ ์ œํ’ˆ์— ๋Œ€ํ•œ ๋ฌธ์„œ๋ฅผ ์ฐพ์•„๋ณด์„ธ์š”.

๋ฌธ์„œ ๋ผ์ด๋ธŒ๋Ÿฌ๋ฆฌ ๋ฐฉ๋ฌธ

์ด๋ฏธ ์—ด๋žŒํ•œ ๊ณ ๊ฐ

Slide 1 of 7

1 of 7

Poly(ethylene glycol) diamine average Mn 10,000

Sigma-Aldrich

752460

Poly(ethylene glycol) diamine

NH2-PEG4-NH2

Sigma-Aldrich

JKA12010

NH2-PEG4-NH2

Methoxypolyethylene glycol amine 2,000, extent of labeling: ≥0.4 mmol/g NH2 loading

Sigma-Aldrich

06676

Methoxypolyethylene glycol amine

Poly(ethylene glycol) diamine average Mn 400

Sigma-Aldrich

909149

Poly(ethylene glycol) diamine

Diamido-dPEG®11-diamine

Sigma-Aldrich

QBD10361

Diamido-dPEGยฎ11-diamine

L Kelemen et al.
Lab on a chip, 19(11), 1985-1990 (2019-05-03)
Whispering gallery mode (WGM) resonators are promising optical structures for microfluidic label-free biosensors mainly due to their high sensitivity, but from a practical point of view they present numerous constraints that make their use in real laboratory diagnosis application difficult.
Urrotigoity, M. and Souppe, J.
Biocatalysis, 2, 145-145 (1989)
K Kawasaki et al.
Chemical & pharmaceutical bulletin, 43(12), 2133-2138 (1995-12-01)
Hybrids of fibronectin-related peptides [Arg-Gly-Asp (RGD), Arg-Gly-Asp-Ser (RGDS)] and poly(ethylene glycol) (PEG) were prepared and their inhibitory effects on experimental metastasis in mice were examined. The inhibitory effect of RGD was markedly potentiated by hybrid formation with poly(ethylene glycol) #6000.
N P Desai et al.
Journal of microencapsulation, 17(6), 677-690 (2000-11-04)
A mixture of alginate and polyethylene glycol acrylate was investigated as a system for the encapsulation of islets of Langerhans. This system showed dual crosslinkability: the alginate was ionically crosslinked by multivalent cations, and the PEG was covalently crosslinked by
Eric Schopf et al.
Chemical communications (Cambridge, England), (32)(32), 4818-4820 (2009-08-05)
A pyrene-functionalized polymer was patterned via electron beam lithography onto a silicon wafer and shown to selectively bind with carbon nanotubes.

๋ฌธ์„œ

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

์กฐ์ง ๊ณตํ•™๊ณผ ์•ฝ๋ฌผ ์ „๋‹ฌ๊ณผ ๊ฐ™์€ ์ƒ๋ช… ๊ณตํ•™์˜ ์ง„๋ณด๋Š” ๋‹ค์–‘ํ•œ ๊ธฐ๋Šฅ์„ฑ ๋ฐ”์ด์˜ค ์†Œ์žฌ์— ๋Œ€ํ•œ ์ˆ˜์š” ์ฆ๊ฐ€๋ฅผ ๋™๋ฐ˜ํ•ฉ๋‹ˆ๋‹ค. ์—ฐ๊ตฌ์˜ ์ง‘์ค‘ ๊ด€์‹ฌ ๋Œ€์ƒ์ด ๋˜์–ด์˜จ ๋ฐ”์ด์˜ค ์†Œ์žฌ์˜ ํ•œ ๋ถ„์•ผ๋Š” ๋ฐ”๋กœ ํ•˜์ด๋“œ๋กœ๊ฒ”์œผ๋กœ, ํ™”ํ•™์ ์œผ๋กœ๋‚˜ ๋ฌผ๋ฆฌ์ ์œผ๋กœ ์„ธํฌ์˜ ์ž์—ฐ ํ™˜๊ฒฝ๊ณผ ์œ ์‚ฌํ•˜๊ฒŒ ๋‹ฎ์•„ ์žˆ๊ธฐ ๋•Œ๋ฌธ์— ์„ธํฌ๋ฅผ ํ‚ค์šฐ๋Š” ํ† ๋Œ€๋กœ ์‚ฌ์šฉ๋  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ๋ณธ ๊ธฐ์ˆ  ๋ฌธ์„œ์—์„œ๋Š” ์ผ๋ฐ˜์ ์œผ๋กœ ๋ฉด์—ญ ๋ฐ˜์‘์„ ์œ ๋ฐœํ•˜์ง€ ๋ชปํ•˜๊ธฐ ๋•Œ๋ฌธ์— ์ƒ๋ฌผํ•™์  ์šฉ๋„๋กœ ์ ํ•ฉํ•œ PEG(ํด๋ฆฌ์—ํ‹ธ๋ Œ ๊ธ€๋ฆฌ์ฝœ) ํ•˜์ด๋“œ๋กœ๊ฒ”์— ๋Œ€ํ•ด ์ƒ์„ธํ•˜๊ฒŒ ๋…ผ์˜ํ•ฉ๋‹ˆ๋‹ค. PEG๋Š” ์‰ฝ๊ฒŒ ์ด์šฉํ•  ์ˆ˜ ์žˆ์œผ๋ฉฐ, ์†์‰ฝ๊ฒŒ ๊ณ ๋ถ„์ž๋ฅผ ์ˆ˜์ •ํ•˜์—ฌ ์„ธํฌ ๋ฐฐ์–‘์„ ์œ„ํ•œ 2D ๋ฐ 3D ๋ผˆ๋Œ€๋ฅผ ํฌํ•จํ•œ ํ•˜์ด๋“œ๋กœ๊ฒ” ๊ตฌ์„ฑ์— ๊ด‘๋ฒ”์œ„ํ•˜๊ฒŒ ์‚ฌ์šฉํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ๋˜ํ•œ ๋ถ„ํ•ด์„ฑ ๊ฒฐํ•ฉ์„ ํ†ตํ•ด ์น˜๋ฃŒ์ œ ์ถœ์‹œ๋ฅผ ์œ„ํ•œ ๋‹ค์–‘ํ•œ ์‘์šฉ๋ถ„์•ผ์—๋„ ๋„์›€์„ ์ค๋‹ˆ๋‹ค.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

์งˆ๋ฌธ

ํ›„๊ธฐ

ํ‰์  ๊ฐ’ ์—†์Œ

ํ™œ์„ฑ ํ•„ํ„ฐ

์ž์‚ฌ์˜ ๊ณผํ•™์žํŒ€์€ ์ƒ๋ช… ๊ณผํ•™, ์žฌ๋ฃŒ ๊ณผํ•™, ํ™”ํ•™ ํ•ฉ์„ฑ, ํฌ๋กœ๋งˆํ† ๊ทธ๋ž˜ํ”ผ, ๋ถ„์„ ๋ฐ ๊ธฐํƒ€ ๋งŽ์€ ์˜์—ญ์„ ํฌํ•จํ•œ ๋ชจ๋“  ๊ณผํ•™ ๋ถ„์•ผ์— ๊ฒฝํ—˜์ด ์žˆ์Šต๋‹ˆ๋‹ค..

๊ณ ๊ฐ์ง€์›ํŒ€์œผ๋กœ ์—ฐ๋ฝ๋ฐ”๋ž๋‹ˆ๋‹ค.