112801
Pyridoxine hydrochloride
98%
동의어(들):
Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C8H11NO3 · HCl
CAS Number:
Molecular Weight:
205.64
Beilstein:
3632435
EC Number:
MDL number:
UNSPSC 코드:
12352005
PubChem Substance ID:
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추천 제품
분석
98%
양식
powder
색상
white to off-white
mp
214-215 °C (lit.)
SMILES string
Cl[H].Cc1ncc(CO)c(CO)c1O
InChI
1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
InChI key
ZUFQODAHGAHPFQ-UHFFFAOYSA-N
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일반 설명
Pyridoxine hydrochloride is a water soluble vitamin. It is available through dietary sources like, meat, fish, nuts, vegetables and fruits.[1]
생화학적/생리학적 작용
Pyridoxine/vitamin B6 is implicated in cellular metabolism, fatty acid biosynthesis, amino acid biosynthesis and catabolism. It is also implicated in the production of neurotransmitters, chlorophyll and plant hormones. Pyridoxine acts as a cofactor for several biochemical reactions.[2] Pyridoxine deficiency is associated with peripheral neuropathy.[3] Pyridoxine hydrochloride is available in parenteral and oral formulations.[1]
Chapter 40 - Nutritional Deficiencies and Syndromes Associated with Alcoholism
Textbook of Clinical Neurology, 897-917 (2007)
Critical Care Toxicology: Diagnosis and Management of the Critically Poisoned Patient (2017)
Vitamin B6 and its role in cell metabolism and physiology
Parra M, et al.
Cells, 7(7), 84-84 (2018)
Ilan Matok et al.
Journal of clinical pharmacology, 53(3), 334-338 (2013-02-28)
Although Diclectin (doxylamine/pyridoxine delayed-released combination) is widely used in Canada, its pharmacokinetics (PK) during pregnancy has never been described. The objective of this study was to compare the PK of doxylamine/pyridoxine delayed-released combination in pregnant versus nonpregnant women. The apparent
Sonia Fargue et al.
Biochimica et biophysica acta, 1832(10), 1776-1783 (2013-04-20)
Primary hyperoxaluria type 1 (PH1) is a rare hereditary calcium oxalate kidney stone disease caused by a deficiency of the liver-specific pyridoxal-phosphate-dependent peroxisomal enzyme alanine:glyoxylate aminotransferase (AGT). About one third of patients are responsive to pharmacological doses of pyridoxine (vitamin
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