Micromachined pits on a substrate can be used to nucleate and stabilize microbubbles in a liquid exposed to an ultrasonic field. Under suitable conditions, the collapse of these bubbles can result in light emission (sonoluminescence, SL). Hydroxyl radicals (OH()) generated
Journal of bioscience and bioengineering, 115(2), 221-228 (2012-10-09)
For efficient production of industrially useful metabolites by microorganisms, it is important to design metabolic networks suitable for production. For this purpose, constraint-based metabolic flux simulation is a powerful tool to predict the effect of reaction knockouts on target productivity.