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Merck

SCN2A

sodium channel, voltage-gated, type II, alpha subunit

동의어:
BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2
:
UniProtKB ID:
Clone ID:
  • Human(6326) Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
  • domestic cat(101080472) sodium channel, voltage-gated, type II, alpha subunit
  • dog(478773) sodium channel, voltage-gated, type II, alpha subunit
  • chicken(395945) sodium channel, voltage-gated, type II, alpha subunit
  • naked mole-rat(101715020) sodium channel, voltage-gated, type II, alpha subunit
  • Horse(100051816) sodium channel, voltage-gated, type II, alpha subunit
  • domestic guinea pig(100716680) sodium channel, voltage-gated, type II, alpha subunit
  • sheep(101103126) sodium channel, voltage-gated, type II, alpha subunit
  • cow(539718) sodium channel, voltage-gated, type II, alpha subunit

Custom & Knockdown Gene Products

Small Molecule - Antagonist

제품 번호
설명
BIA 2-093, ≥98% (HPLC), solid,
rat, human
Oxcarbazepine, ≥98% (HPLC), solid,
rat, human
Riluzole, solid,
rat, human
Lidocaine, analytical standard,
rat, human
Lidocaine, powder,
rat, human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-SCN2A Antibody, clone 5H10.2, clone 5H10.2, from mouse,
종별 반응성
human
응용분야
western blot
Anti-Sodium Channel Antibody, Voltage Gated, Brain Type II, Chemicon®, from rabbit,
종별 반응성
mouse, rat
응용분야
immunohistochemistry
western blot
Anti-SODIUM CHANNEL-PAN antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
종별 반응성
mammals
응용분야
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

제품 번호
설명
Carbamazepine, United States Pharmacopeia (USP) Reference Standard,
human
Phenazopyridine hydrochloride, VETRANAL®, analytical standard,
human
Carbamazepine, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Lidocaine, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Tetracaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Scn2a,
mouse
MISSION® esiRNA, targeting human SCN2A,
human