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Merck

CDK1

cyclin-dependent kinase 1

동의어:
CDC2, CDC28A, P34CDC2
:
UniProtKB ID:
Clone ID:
  • Human(983) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(12534) cyclin-dependent kinase 1
  • Rat(54237) cyclin-dependent kinase 1
  • dog(488997) cyclin-dependent kinase 1
  • Zebrafish(80973) cyclin-dependent kinase 1
  • chicken(396252) cyclin-dependent kinase 1
  • naked mole-rat(101717463) cyclin-dependent kinase 1
  • domestic guinea pig(100735946) cyclin-dependent kinase 1
  • Goat(100861361) cyclin-dependent kinase 1
  • cow(281061) cyclin-dependent kinase 1
  • sheep(100216432) cyclin-dependent kinase 1

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-phospho-CDC2 (pThr161) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot
Anti-Phospho-CDK1-Y15 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-phospho-Cdk1 (Thr14, Tyr15)Antibody, clone CP3.2, clone CP3.2, from mouse,
종별 반응성
human
응용분야
immunocytochemistry
western blot
Anti-Cdc2 Antibody, phospho-specific (Tyr15), Chemicon®, from rabbit,
종별 반응성
rat
응용분야
western blot
Rabbit anti-CDK1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
종별 반응성
human
응용분야
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

제품 번호
설명
R547, ≥98% (HPLC),
human
Flavopiridol hydrochloride hydrate, ≥98% (HPLC), powder,
human
Roscovitine, ≥98% (TLC),
human, mouse, rat

Proteins

제품 번호
설명
CDK1/CyclinB1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human
CDK1/Cyclin A2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human CDK1,
human