CASP3
caspase 3, apoptosis-related cysteine peptidase
동의어:
CPP32, CPP32B, SCA-1
종:
Human CASP3 (836), Mouse Casp3 (12367), Rat Casp3 (25402), dog CASP3 (403567), chicken CASP3 (395476), naked mole-rat Casp3 (101712867), domestic guinea pig Casp3 (100718309), cow CASP3 (408016), Domestic Rabbit CASP3 (100008840), sheep CASP3 (443031) ...더
UniProtKB ID:
Clone ID:
- Human(836) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
- Mouse(12367) caspase 3
- Rat(25402) caspase 3
- dog(403567) caspase 3, apoptosis-related cysteine peptidase
- chicken(395476) caspase 3, apoptosis-related cysteine peptidase
- naked mole-rat(101712867) caspase 3, apoptosis-related cysteine peptidase
- domestic guinea pig(100718309) caspase 3, apoptosis-related cysteine peptidase
- cow(408016) caspase 3, apoptosis-related cysteine peptidase
- Domestic Rabbit(100008840) caspase 3, apoptosis-related cysteine peptidase
- sheep(443031) caspase 3, apoptosis-related cysteine peptidase
- domestic cat(493932) caspase 3, apoptosis-related cysteine peptidase
- Horse(100034083) caspase 3, apoptosis-related cysteine peptidase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Activity Assay
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-CASP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CASP3 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot
western blot
Anti-CASP3 antibody produced in rabbit, IgG fraction of antiserum,
종별 반응성
human
응용분야
immunohistochemistry
western blot
western blot
Anti-Caspase 3 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
종별 반응성
human
응용분야
microarray
western blot
western blot
Anti-CASP3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
canine, human, mouse, rat
응용분야
ELISA
western blot
western blot
Small Molecule - Inhibitor
Proteins
제품 번호
설명
종
Caspase 3 human, ≥85% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous glycerol solution, ≥1.0 units/mg protein,
종
human
esiRNA
제품 번호
설명
종