T0647

TAPS sodium salt

≥99% (titration)

• Synonym(s): 3-[N,N-Bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic acid sodium salt, TAPS NA, N-tris(Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium-potassium salt, [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid sodium-potassium salt
• Empirical Formula (Hill Notation): C₇H₁₆NNaO₆S
• CAS Number: 91000-53-2
• Molecular Weight: 265.26
• MDL number: MFCD00069903
• UNSPSC Code: 12161700
• PubChem Substance ID: 24899903
• NACRES: NA.25

Properties

• Assay: ≥99% (titration)
• form: crystalline powder
• impurities: ≤1% water content (Karl Fischer)
• useful pH range: 7.7-9.1
• pKa (25 °C): 8.4
• solubility: water: 0.33 g/mL, clear to slightly hazy, colorless
• cation traces: Pb: ≤5 ppm
• application(s): diagnostic assay manufacturing
• SMILES string: [Na+].OCC(CO)(CO)NCCCS([O-])(=O)=O
• InChI: 1S/C7H17NO6S.Na/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14;/h8-11H,1-6H2,(H,12,13,14);/q;+1/p-1
• InChI key: FEGYIWVHCSRXCG-UHFFFAOYSA-M

Description

General description

N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid (TAPS) is a zwitterionic ionic buffer that is widely used in capillary electrophoresis. As one of the key biological buffers, it maintains the required pH of the medium and exhibits various properties such as high water soluble, highly inert, and stable nature and extremely low absorbance of ultraviolet-visible (UV-vis) light. TAPS buffer also aids in stabilizing lysozyme against thermal denaturation. It is widely used in biology and biochemistry.

Application

TAPS sodium salt has been used along with filtered natural sea water (FSW) to stain live or fixed embryos.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves