T9269

TAPSO

≥99% (titration)

• Synonym(s): 2-Hydroxy-3-[tris(hydroxymethyl)methylamino]-1-propanesulfonic acid, N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid
• Empirical Formula (Hill Notation): C₇H₁₇NO₇S
• CAS Number: 68399-81-5
• Molecular Weight: 259.28
• Beilstein: 2113949
• EC Number: 269-993-8
• UNSPSC Code: 12161700
• PubChem Substance ID: 24900590
• NACRES: NA.25

Properties

• Assay: ≥99% (titration)
• form: crystalline powder
• useful pH range: 7.0-8.2
• pKa (25 °C): 7.6
• solubility: warm water: 0.333 g/mL, clear to slightly hazy, colorless
• application(s): diagnostic assay manufacturing
• SMILES string: OCC(CO)(CO)NCC(O)CS(O)(=O)=O
• InChI: 1S/C7H17NO7S/c9-3-7(4-10,5-11)8-1-6(12)2-16(13,14)15/h6,8-12H,1-5H2,(H,13,14,15)
• InChI key: RZQXOGQSPBYUKH-UHFFFAOYSA-N

Description

Application

• Interpretation of non-Nernstian slopes in graphic analysis of data collected in pH range close to deprotonation of a ligand Part I. A glass electrode potentiometric and polarographic study of Cd-(TAPSO)x-(OH)y and Zn-(TAPSO)x-(OH)y systems.: Explores the complex behavior of TAPSO in metal binding studies, particularly with cadmium and zinc, providing insight into its utility in heavy metal chelation and environmental cleanup strategies (Machado et al., 2006).


• Challenges in modelling and optimisation of stability constants in the study of Cu-(TAPS)(x)-(OH)(y) system by polarography.: Discusses the challenges in modeling and optimizing the stability constants for copper complexes with TAPSO, contributing to better understanding and utilization of this buffer in copper-related biochemical research (Machado and Soares, 2007).


• Modelling of Pb-(TAPS)(x)-(OH)(y) system and refinement of stability constants in the region of lead hydrolysis and lead hydroxide precipitation.: Provides a detailed examination of TAPSO′s role in modeling lead complexation systems, which is critical for environmental monitoring and remediation efforts involving lead (Machado et al., 2007).


• Synthetic organic pH buffers can support fertilization of guinea pig eggs, but not as efficiently as bicarbonate buffer.: Evaluates the efficacy of synthetic buffers like TAPSO in supporting fertilization, offering valuable data for reproductive biology and assisted reproductive technologies (Bhattacharyya and Yanagimachi, 1988).

Caution

According to Ferreira, et al., TAPSO can have a strong interaction with iron in solution. Based on this citation, it is recommended to use plastic-coated or PTFE-coated utensils when working with this chemical.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves